Table 4 Prognostic factors for GBC and results of multivariate Cox regression analysis

Age

26–45

1

-

Reference

46–65

0.955

0.642–1.422

0.822

Region

Rural

1

-

Reference

Urban

1.568

1.020–2.410

0.040*

Jaundice

Absent

1

-

Reference

Present

1.087

0.775–1.523

0.629

Gallstone

Absent

1

-

Reference

Present

1.571

1.002–2.464

0.049*

Liver infiltration

Absent

1

-

Reference

Present

1.448

0.735–2.853

0.285

Grade

I/II

1

-

Reference

III/IV

1.144

0.822–1.591

0.425

Clinical stage

I/II

1

-

Reference

III/IV

0.658

0.300–1.444

0.296

Tumor stage

T1/T2

1

-

Reference

T3/T4

1.794

0.987–3.264

0.055

N stage

N0

1

-

Reference

N1/N2

1.468

1.041–2.070

0.029*

M stage

M0

1

-

Reference

M1

2.289

1.529–3.425

< 0.0001**

Surgery

No

1

-

Reference

Yes

0.573

0.346–0.948

0.030*

Radiation

No

1

-

Reference

Yes

0.573

0.286–1.149

0.117