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Table 5 Univariate analysis of variables associated with the incidence of anastomotic leakage

From: Indocyanine green fluorescence imaging during laparoscopic rectal cancer surgery could reduce the incidence of anastomotic leakage: a single institutional retrospective cohort study

  

AL ( +)

p-value

OR (95% CIs)

Sex

Male

14/123 (11.4%)

0.083

2.611 (0.821–9.447)

Female

3/64 (4.7%)

Age, years

 ≥ 70

4/70 (5.7%)

0.210

0.484 (0.151–1.550)

 < 70

13/117 (11.1%)

BMI

 > 25

2/27 (7.4%)

0.394

0.506 (0.106–2.419)

 < 25

12/88 (13.6%)

Tumor location

Low

11/78 (14.1%)

0.051

2.818 (0.994–7.983)

Upper, middle

6/109 (5.5%)

Tumor staging

Stages I and II

11/99 (11.1%)

0.312

1.708 (0.604–4.829)

Stages III and IV

6/88 (6.8%)

Neoadjuvant therapy

 + 

2/18 (11.1%)

0.754

1.283 (0.268–6.123)

 − 

15/169 (8.9%)

Surgical procedure

LAR, ISR

14/136 (10.3%)

0.330

1.836 (0.504–6.675)

HAR

3/51 (5.9%)

Operating time (min)

 ≥ 360

10/68 (14.7%)

0.048

2.758 (1.023–7.624)

 < 360

7/119 (5.9%)

Blood loss (mL)

 ≥ 100

6/52 (11.5%)

0.472

1.470 (− 0.514–4.204)

 < 100

11/135 (8.2%)

Transanal tube

 − 

10/111 (9%)

0.962

0.975 (0.354–2.688)

 + 

7/76 (9.2%)

Diverting stoma

 − 

12/116 (10.3%)

0.448

1.523 (0.513–4.520)

 + 

5/71 (7%)

ICG fluorescence imaging

 − 

14/114 (12.3%)

0.046

3.266 (1.038–11.793)

 + 

3/73 (4.1%)

  1. BMI body mass index, ICG indocyanine green, HAR high anterior resection, LAR low anterior resection, ISR intersphincteric resection, AL anastomotic leakage, OR odds ratio, CI confidence interval