Skip to main content

Table 3 Univariate Cox regression model for PPS in 117 patients

From: Analyzing the role of reoperation in recurrent glioblastoma: a 15-year retrospective study in a single institution

Variable of interest

No. of events/no. of patients (n = 117)

HR (CI 95%)

p value

Age (years)

  

0.235

   < 58

53/56

0.89 (0.73–1.07)

 

   ≥ 58

58/61

1

 

First surgery date

  

0.021

  Recent (2012–2019)

77/83

0.61 (0.40–0.92)

 

  Old (2005–2011)

34/34

1

 

Resection at first surgery

  

0.492

  GTR

83/87

0.85 (0.55–1.32)

 

  STR

28/30

1

 

Chemotherapy

  

0.791

  Complete Stupp

63/68

0.95 (0.64–1.38)

 

  Incomplete Stupp

47/49

1

 

ECOG 1

  

0.219

  Asymptomatic/mild

94/100

0.71 (0.42–1.21)

 

  Symptomatic

17/17

1

 

ECOG 2

  

0.002

  Asymptomatic/mild

67/72

0.52 (0.35–0.78)

 

  Symptomatic

44/45

1

 

PFS (months)

  

0.836

   ≥ 10

54/59

0.96 (0.65–1.40)

 

   < 10

57/58

1

 

Treatment groups

  

0.166

  Reintervention

29/33

0.73 (0.47–1.13)

 

  Chemotherapy

82/84

1

 
  1. GTR gross total resection, STR subtotal resection, ECOG 1 ECOG after the first procedure, ECOG 2 ECOG at progression, PFS progression-free survival