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Table 4 The list of the more significant PLS-DA model biomarkers linked to cancer grades

From: The amino acid and carnitine concentration changes in bronchoalveolar lavage fluid from lung cancer patients

Metabolite

Non-cancer (n = 22)

Lung cancer

Grades I & II (n = 6)

Grades III & IV (n = 16)

p value

Mean ± SD

Mean ± SD

Mean ± SD

Asp

8.81 ± 3.51

6.58 ± 2.00

6.87 ± 1.79

0.033

Glu

11.15 ± 3.91

8.20 ± 1.95

8.51 ± 1.28

0.027

Ser

2.40 ± 1.05

3.14 ± 0.22

3.34 ± 1.36

0.017

C4DC

0.05 ± 0.02

0.02 ± 0.02

0.01 ± 0.02

0.013

C26

0.01 ± 0.01

0.01 ±  < 0.01

0.01 ±  < 0.01

 < 0.001

C26/C20

0.11 ± 0.21

0.31 ± 0.10

0.23 ± 0.18

0.003

  1. The data are presented as mean ± standard deviation: amine acid and carnitine unit was μmol/L; p value the statistical significance between the grades I & II group and the grades III & IV group was assessed using the Mann–Whitney U test. p < 0.05 indicates significance and p < 0.01 indicates more significance for statistical analysis. Due to reserving two decimal places, the data related to C26 in this table are not clear. The C26 level of non-cancer group is 0.007 ± 0.010 μmol/L, its grades I & II 0.012 ± 0.004 μmol/L and grades III & IV 0.009 ± 0.004 μmol/L
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World Journal of Surgical Oncology

ISSN: 1477-7819

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