Metabolite | VIP value | Lung cancer | Non-cancer | p value* | ||
---|---|---|---|---|---|---|
Mean ± SD | p value | Mean ± SD | p value | |||
Hcy | 2.94 | 8.45 ± 0.38 | < 0.001 | 8.81 ± 0.39 | 0.005 | 0.001 |
Ser | 2.59 | 3.29 ± 1.16 | < 0.001 | 2.40 ± 1.05 | 0.002 | < 0.001 |
Asn | 2.59 | 28.84 ± 5.39 | < 0.001 | 37.18 ± 4.09 | 0.059 | < 0.001 |
Cys | 2.41 | 1.26 ± 0.33 | < 0.001 | 2.77 ± 3.43 | < 0.001 | 0.001 |
C26 | 2.37 | 0.01 ± < 0.01 | < 0.001 | 0.01 ± 0.01 | < 0.001 | 0.001 |
Lys | 2.16 | 10.52 ± 1.92 | < 0.001 | 42.93 ± 78.79 | < 0.001 | 0.048 |
C26/C20 | 1.82 | 0.25 ± 0.16 | < 0.001 | 0.11 ± 0.21 | < 0.001 | 0.001 |
C20 | 1.58 | 0.02 ± 0.01 | < 0.001 | 0.02 ± 0.02 | 0.001 | 0.937 |
C6DC | 1.47 | 0.06 ± 0.14 | < 0.001 | 0.09 ± 0.17 | < 0.001 | 0.864 |
Trp | 1.39 | 5.21 ± 1.07 | < 0.001 | 6.80 ± 2.38 | 0.003 | 0.001 |
C5DC/C8 | 1.35 | 0.56 ± 0.62 | < 0.001 | 0.54 ± 0.83 | < 0.001 | 0.043 |
C5-OH/C8 | 1.33 | 0.84 ± 0.64 | < 0.001 | 0.57 ± 0.56 | 0.001 | 0.025 |
C4DC | 1.31 | 0.03 ± 0.02 | < 0.001 | 0.05 ± 0.02 | 0.003 | 0.001 |
C5DC/C16 | 1.31 | 0.26 ± 0.23 | 0.001 | 0.46 ± 0.83 | < 0.001 | 0.590 |
C22 | 1.30 | 0.01 ± 0.01 | < 0.001 | 0.02 ± 0.03 | < 0.001 | 0.433 |
Glu | 1.24 | 8.43 ± 1.45 | < 0.001 | 11.15 ± 3.91 | 0.045 | 0.001 |
Asp | 1.12 | 6.79 ± 1.81 | < 0.001 | 8.81 ± 3.51 | 0.009 | 0.002 |
Gln | 1.11 | 1.07 ± 0.26 | < 0.001 | 2.68 ± 3.57 | < 0.001 | 0.002 |
C5DC/C5-OH | 1.10 | 0.91 ± 1.14 | < 0.001 | 0.17 ± 0.32 | < 0.001 | 0.002 |
C5DC | 1.06 | < 0.01 ± < 0.01 | < 0.001 | 0.02 ± < 0.01 | < 0.001 | 0.127 |
C12 | 1.05 | 0.01 ± 0.02 | < 0.001 | 0.03 ± 0.04 | < 0.001 | 0.022 |
C3DC/C10 | 1.05 | 0.37 ± 0.29 | < 0.001 | 0.33 ± 0.27 | 0.005 | 0.149 |
His | 1.05 | 7.84 ± 6.50 | < 0.001 | 9.35 ± 13.69 | < 0.001 | 0.360 |
Tyr/Cit | 1.01 | 3.89 ± 8.26 | < 0.001 | 2.38 ± 2.55 | 0.001 | 0.851 |