Table 3 Univariable and multivariable analyses to determine independent predictors of overall survival of primary retroperitoneal liposarcoma
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | |
Gender (male vs. female) | 6.342 (0.818–49.159) | 0.077 | 2.034 (0.203–20.361) | 0.546 |
Age | 1.020 (0.968–1.076) | 0.460 | 0.996 (0.936–1.06) | 0.893 |
BMI | 0.915 (0.785–1.066) | 0.256 | ||
ALB | 0.994 (0.902–1.095) | 0.902 | ||
PALB | 2.856 (0.003–2974.716) | 0.767 | ||
A/G | 0.695 (0.163–2.961) | 0.622 | ||
Hb | 0.996 (0.965–1.029) | 0.814 | ||
SCr | 1.044 (1.020–1.068) | < 0.001* | 1.043 (1.011–1.076) | 0.008* |
SMA | 1.006 (0.988–1.024) | 0.513 | ||
SMI | 1.007 (0.947–1.072) | 0.820 | ||
PMA | 1.012 (0.907–1.129) | 0.829 | ||
PMI | 0.967 (0.677–1.381) | 0.853 | ||
Fat area | 0.995 (0.980–1.010) | 0.511 | ||
Sarcopenia (yes vs. no) | 1.537 (0.463–5.106) | 0.483 | 1.494 (0.363–6.151) | 0.578 |
Symptoms (yes vs. no) | 3.954 (1.070–14.613) | 0.039* | 4.371 (1.018–18.768) | 0.047* |
Histologic subtypes | 0.638 | |||
MLPS vs. WDLPS | 1.368 (0.165–11.373) | |||
DDLPS vs. WDLPS | 2.198 (0.671–7.203) | |||
PLPS vs. WDLPS | 0 (0–0) | |||
FNCLCC | 0.150 | 0.571 | ||
Grade 2 vs. 1 | 1.557 (0.348–6.962) | 2.087 (0.384–11.351) | ||
Grade 3 vs. 1 | 3.827 (0.914–16.024) | 2.37 (0.427–13.159) | ||
Tumor burden | 0.987 (0.928–1.050) | 0.676 | ||
Combined-organ resection (yes vs. no) | 1.583 (0.347–7.226) | 0.553 | ||
Operation duration | 1.082 (0.736–1.592) | 0.688 | ||
Estimated blood loss | 1 (1.000–1.001) | 0.398 | ||
Blood transfusion (yes vs. no) | 1.928 (0.612–6.075) | 0.262 | ||
ICU stay (yes vs. no) | 39.955 (0.279–5724.408) | 0.145 | ||
Postoperative hospital stays | 1.024 (1.006–1.041) | 0.008* | 1.004 (0.984–1.025) | 0.677 |
Complication (yes vs. no) | 1.271 (0.403–4.007) | 0.682 | ||