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Table 2 Clinicopathological characteristics of patients with adeno-NEPC

From: Clinicopathological and immunological profiles of prostate adenocarcinoma and neuroendocrine prostate cancer

Characteristic

Only SYN (+)

n = 12

Not only SYN (+)

n = 8

P

Age (years)

66.00 ± 2.00

72.63 ± 2.12

0.041

T staging

  

0.528

 T2

3 (25.0%)

1 (12.5%)

 

 T3

8 (66.7%)

5 (62.5%)

 

 T4

1 (8.3%)

2 (25.0%)

 

N staging

  

0.142

 N0

7 (58.3%)

2 (25.0%)

 

 N1

5 (41.7%)

6 (75.0%)

 

M staging

  

0.852

 M0

7 (58.3%)

5 (62.5%)

 

 M1

5 (41.7%)

3 (37.5%)

 

Gleason score

  

0.798

 ≤ 7

2 (16.7%)

1 (12.5%)

 

 > 7

10 (83.3%)

7 (87.5%)

 

PSA (ng/L)

  

0.224

 ≤ 20

2 (16.7%)

0 (0.0%)

 

 > 20

10 (83.3%)

8 (100.0%)

 

LDH (U/L)

  

0.999

 < 250

9 (75.0%)

6 (75.0%)

 

 ≥ 250

3 (25.0%)

2 (25.0%)

 

ALP (U/L)

  

0.798

 < 125

10 (83.3%)

7 (87.5%)

 

 ≥ 125

2 (16.7%)

1 (12.5%)

 
  1. Abbreviations: SYN Synaptophysin, PSA Prostate-specific antigen, LDH Lactate dehydrogenase, ALP Alkaline phosphatase