Fig. 4

PD-L1 expression in adeno-NEPC and its possible negative correlation with CD8+ T-cell expression. a Heat map used to describe the distribution and expression of PD-L1 in each adeno-NEPC sample. b Histogram used to demonstrate a trend toward a higher PD-L1 score (2–4) in metastatic PCa. c Histogram used to demonstrate a trend toward a lower expression of CD8⁺ T cells in patients with higher PD-L1 scores (2–4). PD-L1, programmed death-ligand 1