Skip to main content

Table 1 Demographic features and association between PLR and clinical features

From: Defining the impact of platelet-to-lymphocyte ratio on patient survival with gastric neuroendocrine neoplasm: a retrospective cohort analysis

Variables

Total (n = 238)

Q1 (n = 60)

Q2 (n = 60)

Q3 (n = 60)

Q4 (n = 58)

P value

(38–349)

< 103

> = 103–< 137

>= 137–< 187

> = 187

PLR

152.64 ± 65.11

82.13 ± 16.03

121.51 ± 10.35

164.25 ± 14.34

245.78 ± 42.60

< 0.001

Sex

 Male

179 (75.21%)

42 (70.00%)

45 (75.00%)

51 (85.00%)

41 (70.69%)

0.204

 Female

59 (24.79%)

18 (30.00%)

15 (25.00%)

9 (15.00%)

17 (29.31%)

 

Age (years)

Continuous

60.26 ± 10.09

58.18 ± 9.77

59.17 ± 10.86

62.78 ± 9.55

60.95 ± 9.76

0.063

 <= 60

119 (50.00%)

34 (56.67%)

33 (55.00%)

25 (41.67%)

27 (46.55%)

0.307

 > 60

119 (50.00%)

26 (43.33%)

27 (45.00%)

35 (58.33%)

31 (53.45%)

 

BMI (kg/m2)

Continuous

24.05 ± 3.35

24.66 ± 3.40

24.54 ± 3.14

23.64 ± 2.97

23.33 ± 3.76

0.076

 < 25

139 (58.40%)

31 (51.67%)

29 (48.33%)

39 (65.00%)

40 (68.97%)

0.061

 >= 25

99 (41.60%)

29 (48.33%)

31 (51.67%)

21 (35.00%)

18 (31.03%)

 

Smoking status

 No

147 (61.77%)

43 (71.67%)

33 (55.00%)

33 (55.00%)

38 (65.52%)

0.16

 Yes

91 (38.23%)

17 (28.33%)

27 (45.00%)

27 (45.00%)

20 (34.48%)

 

Operative approach

 MIS

83 (34.87%)

28 (46.67%)

27 (45.00%)

13 (21.67%)

15 (25.86%)

0.004

 Open surgery

155 (65.13%)

32 (53.33%)

33 (55.00%)

47 (78.33%)

43 (74.14%)

 

Tumor size (cm)

 Continuous

4.24 ± 2.79

2.94 ± 1.91

3.90 ± 2.39

4.73 ± 2.95

5.45 ± 3.18

< 0.001

 <= 4.0

112 (47.06%)

44 (73.33%)

28 (46.67%)

26 (43.33%)

14 (24.14%)

< 0.001

 > 4.0

126 (52.94%)

16 (26.67%)

32 (53.33%)

34 (56.67%)

44 (75.86%)

 

CgA

 Negative

127 (53.36%)

31 (51.67%)

33 (55.00%)

30 (50.00%)

33 (56.90%)

0.874

 Positive

111 (46.64%)

29 (48.33%)

27 (45.00%)

30 (50.00%)

25 (43.10%)

 

Syn

 Negative

28 (11.76%)

8 (13.33%)

5 (8.33%)

9 (15.00%)

6 (10.34%)

0.673

 Positive

210 (88.24%)

52 (86.67%)

55 (91.67%)

51 (85.00%)

52 (89.66%)

 

Tumor type

 NET

51 (21.43%)

18 (30.00%)

18 (30.00%)

7 (11.67%)

8 (13.79%)

0.015

 NEC

137 (57.56%)

27 (45.00%)

31 (51.67%)

37 (61.67%)

42 (72.41%)

 

 MiNEN

50 (21.01%)

15 (25.00%)

11 (18.33%)

16 (26.67%)

8 (13.79%)

 

Grade

 G1–G2

62 (26.05%)

23 (38.33%)

17 (28.33%)

12 (20.00%)

10 (17.24%)

0.04

 G3

176 (73.95%)

37 (61.67%)

43 (71.67%)

48 (80.00%)

48 (82.76%)

 

T stage

     

0.17

 T1–T2

71 (29.83%)

23 (38.33%)

20 (33.33%)

16 (26.67%)

12 (20.69%)

 

 T3–T4

167 (70.17%)

37 (61.67%)

40 (66.67%)

44 (73.33%)

46 (79.31%)

 

N stage

 N0

77 (32.35%)

21 (35.00%)

21 (35.00%)

21 (35.00%)

14 (24.14%)

0.5

 N1–3

161 (67.65%)

39 (65.00%)

39 (65.00%)

39 (65.00%)

44 (75.86%)

 

M stage

 M0

193 (81.09%)

53 (88.33%)

49 (81.67%)

49 (81.67%)

42 (72.41%)

0.177

 M1

45 (18.91%)

7 (11.67%)

11 (18.33%)

11 (18.33%)

16 (27.59%)

 

Tumor stage

 I–II

93 (39.08%)

27 (45.00%)

26 (43.33%)

23 (38.33%)

17 (29.31%)

0.298

 III–IV

145 (60.92%)

33 (55.00%)

34 (56.67%)

37 (61.67%)

41 (70.69%)

 

Chemotherapy

 No

182 (76.47%)

42 (70.00%)

44 (73.33%)

53 (88.33%)

43 (74.14%)

0.086

 Yes

56 (23.53%)

18 (30.00%)

16 (26.67%)

7 (11.67%)

15 (25.86%)

 
  1. Abbreviations: PLR platelet to lymphocyte ratio, Q interquartile range, BMI body mass index, MIS minimally invasive surgery, CgA chromogranin, Syn synaptophysin, NET neuroendocrine tumor, NEC neuroendocrine carcinoma, MiNEN mixed neuroendocrine/non-neuroendocrine neoplasm