Advanced gastric cancer | |||||||
---|---|---|---|---|---|---|---|
All | (n = 76) | Open | (n = 37) | Lap | (n = 39) | p | |
Pathological features | |||||||
Site | 0.10 | ||||||
Pylorus or antrum | 70 | (92) | 32 | (86) | 38 | (97) | |
Low body | 6 | (7.9) | 5 | (14) | 1 | (2.6) | |
Size (cm) | 5.0 | (3.22–6.5) | 5.5 | (4–7) | 4.5 | (3.15–6) | 0.10 |
Bormann type | 0.075 | ||||||
Early gastric cancer | 1 | (1.3) | 0 | (0) | 1 | (2.6) | |
I or II | 17 | (22) | 5 | (14) | 12 | (31) | |
III or IV | 58 | (76) | 32 | (86) | 26 | (67) | |
Lauren classification | 0.99 | ||||||
Intestinal type | 56 | (74) | 28 | (76) | 28 | (72) | |
Diffuse type | 12 | (16) | 5 | (14) | 7 | (18) | |
Mixed type | 8 | (11) | 4 | (11) | 4 | (10) | |
Cell differentiation | 0.70 | ||||||
Well differentiated | 8 | (11) | 4 | (11) | 4 | (10) | |
Moderately differentiated | 39 | (51) | 17 | (46) | 22 | (56) | |
Poorly or undifferentiated | 29 | (38) | 16 | (43) | 13 | (33) | |
LN metastasis (number) | 4 | (1–8) | 5 | (1–10) | 4 | (2–8) | 0.90 |
LN harvested (number) | 39 | (29–48) | 42 | (29–52) | 37 | (30–45) | 0.30 |
Lymphovascular invasion | 53 | (70) | 26 | (70) | 27 | (69) | 0.99 |
Perineural invasion | 39 | (51) | 25 | (68) | 14 | (36) | 0.007* |
Pathological T stage (AJCC 8th) | 0.5 | ||||||
1 | 5 | (6.6) | 1 | (2.7) | 4 | (10) | |
2 | 15 | (20) | 6 | (16) | 9 | (23) | |
3 | 34 | (45) | 18 | (49) | 16 | (41) | |
4 | 22 | (29) | 12 | (32) | 10 | (26) | |
Pathological N stage (AJCC 8th) | 0.20 | ||||||
0 | 10 | (13) | 7 | (19) | 3 | (7.7) | |
1 | 17 | (22) | 7 | (19) | 10 | (26) | |
2 | 23 | (30) | 8 | (22) | 15 | (38) | |
3 | 26 | (34) | 15 | (41) | 11 | (28) | |
Pathological stage (AJCC 8th) | 0.8 | ||||||
II | 36 | (47) | 17 | (46) | 19 | (49) | |
III | 40 | (53) | 20 | (54) | 20 | (51) | |
Short-term and long-term outcomes | |||||||
Operative time (min) | 206 | (178–228) | 192 | (165–212) | 215 | (190–238) | 0.006* |
Blood loss (mL) | 100 | (0–200) | 100 | (0–200) | 100 | (0–150) | 0.059 |
Complications (≥ grade 3) | 10 | (13) | 5 | (14) | 5 | (13) | 0.99 |
Length of postoperative hospitalization (d) | 12 | (10–16) | 13 | (11–22) | 11 | (10–14.5) | 0.042* |
Follow-up (mo) | 22 | (12–38) | 27 | (15–44) | 15 | (10–32) | 0.03* |
Three-year RFS (%) | 58.6 | (47.9–71.7) | 51.0 | (37.1–70.1) | 66.2 | (51.1–85.7) | 0.10 |