Table 4 Studies on regrowth and salvage surgery
Study | Patients (WW group), n | Regrowth rate | Salvage rate | Salvage type | Pathology of LE group | Follow-up, months | OS/DFS (patients with regrowth) |
|---|---|---|---|---|---|---|---|
Habr-Gama et al. [27] | 90 | 28 (31%) | 93% | LAR: 7 (26%) APR: 11 (42%) LE: 7 (26%) BRACYTX: 1 (1%) | T1: 2 (28.5%) T2: 5 (71.5%) | 60 | 88%/78% |
van der Valk et al. [28] | 880 | 213 (24%) | 69% | TME: 78% LE: 31% | NR | 40 | 75.4%/NR |
Smith et al. [29] | 113 | 22 (19%) | 100% | LAR: 9 (41%) APR: 10 (45%) LE: 2 (0.9%) Perineal Resection: 1 (0.4%) | T1: 1 NR: 1 | 43 | NR/NR |
Nasir et al. [14] | 78 | 23 (29%) | 100% | LAR: 10 (43.5%) APR: 9 (39.1%) LE: 4 (17.4%) | T0: 1 (75%) T2: 3 (25%) | 36 | NR/NR |
Fernandez et al. [30] | 257 | 73 (28%) | 94% | LAR: 19 (27%) APR: 24 (34%) LE: 22 (31%) BRACYTX: 1 (0.1%) NR: 3 (0.4%) | NR | 40 | NR/NR |
van der Sande et al. [31] | 385 | 89 (23%) | 94% | LAR: 34 (40%) APR: 24 (27%) LE: 26 (31%) | T0: 5 (19%) T1: 4 (15%) T2: 15 (58%) T3: 1 (4%) Tx: 1 (4%) | 28 | 98.4%/90.3% |
Geubels et al. [32] | 591 | 175 (29%) | 94% | TME: 89 (50%) LE: 77 (44%) | T0: 28 (36%) T1: 11 (14%) T2: 32 (41%) T3: 6 (0.7%) | 53 | 96%/NR |
Present study | 39 | 10 (25%) | 100% | LAR: 3 (30%) APR: 2 (20%) LE: 5 (50%) | T2: 4 (80%) T3: 1 (20%) | 63 | 95%/80% |