Fig. 2

Localization and expression of NPM2 protein in MPM. A1–A4 Loss of NPM2 protein expression. B1–B4 NPM2 protein localized to the cytoplasm. C1–C4 NPM2 protein localized to the nucleus. D1–D4 Different cellular components and their staining intensity were classified by QuPath-0.3.2 software. The red, orange, yellow, and blue were all tumor cells, but the staining intensity of NPM2 protein was strongly positive, moderately positive, weakly positive, and negative, respectively. The light green was stromal cells, and the staining intensity of NPM2 protein was negative (1: ×40; 2: ×100; 3: ×200; 4: ×400)