Table 4 Mean location, distribution, and total scores in Col1, Col4, a-SMA, and MMP-9

Location score

Non-metastatic tumors (N0T)

1.05

1.40*

1.74*

1.52*

Metastatic tumors (TN1T)

1.10

1.37*

1.79*

1.55*

Metastatic lymph nodes (N1N)

1.10

1.58*

1.79*

1.63*

Distribution score

Non-metastatic tumors (N0T)

2.38*

1.84*

1.34

1.44

Metastatic tumors (N1T)

1.55

0.68

1.37

2.00

Metastatic lymph nodes (N1N)

1.66

0.71

1.82

1.92

Total score

Non-metastatic tumors (N0T)

5.00*

4.32**

3.18

2.88

Metastatic tumors (N1T)

4.13 + 

2.74

3.21

3.53 + 

Metastatic lymph nodes (N1N)

4.32 + 

2.60

3.82

3.45 +