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Table 5 Relationship between of IL1B expression and clinical characteristics of patients with CESC

From: Identification of a necroptosis-related prognostic gene signature associated with tumor immune microenvironment in cervical carcinoma and experimental verification

Gene

Characteristics

Total (N)

Odds ratio (OR)

P value

IL1B

Age (≤ 50 vs. > 50)

304

1.043 (0.902–1.209)

0.573

BMI (≤ 25 vs. > 25)

259

1.136 (0.966–1.339)

0.124

Menopause status (Pre vs. Peri and Post)

231

1.121 (0.949–1.331)

0.183

Histological type (adenosquamous vs. squamous cell carcinoma)

304

0.489 (0.361–0.640)

 < 0.001

T stage (T1 and T2 vs. T3 and T4)

241

0.719 (0.572–0.900)

0.004

N stage (N0 vs. N1)

193

1.045 (0.857–1.284)

0.668

M stage (M0 vs. M1)

126

1.073 (0.715–1.731)

0.751

Clinical stage (stage I and stage II vs. stage IV and stage III)

297

0.846 (0.717–1.000)

0.048

Histologic grade (G1 and G2 vs. G4 and G3)

272

0.892 (0.763–1.041)

0.149

Primary therapy outcome (SD and PR and CR vs. PD)

217

0.758 (0.588–0.980)

0.031

Radiation therapy (yes vs. no)

304

0.977 (0.847–1.130)

0.756

  1. Abbreviations: CESC cervical squamous cell carcinoma and endocervical adenocarcinoma, PD progressive disease, CR complete response, SD stable disease, PR partial response, BMI body mass index