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Table 4 Relationship between of IL1A expression and clinical characteristics of patients with CESC

From: Identification of a necroptosis-related prognostic gene signature associated with tumor immune microenvironment in cervical carcinoma and experimental verification

Gene

Characteristics

Total (N)

Odds ratio (OR)

P value

IL1A

Age (≤ 50 vs. > 50)

304

1.153 (1.029–1.298)

0.016

BMI (≤ 25 vs. > 25)

259

1.076 (0.953–1.215)

0.238

Menopause status (Pre vs. Peri and Post)

231

1.182 (1.040–1.351)

0.012

Histological type (adenosquamous vs. squamous cell carcinoma)

304

0.234 (0.140–0.357)

 < 0.001

T stage (T1 and T2 vs. T3 and T4)

241

0.877 (0.738–1.047)

0.138

N stage (N0 vs. N1)

193

0.997 (0.861–1.158)

0.963

M stage (M0 vs. M1)

126

1.004 (0.743–1.419)

0.980

Clinical stage (Stage I and stage II vs. stage IV and stage III)

297

0.893 (0.787–1.015)

0.080

Histologic grade (G1 and G2 vs. G4 and G3)

272

1.088 (0.967–1.227)

0.164

Primary therapy outcome (SD and PR and CR vs. PD)

217

0.819 (0.675–0.995)

0.042

Radiation therapy (yes vs. no)

304

0.988 (0.886–1.103)

0.827

  1. Abbreviations: CESC cervical squamous cell carcinoma and endocervical adenocarcinoma, PD progressive disease, CR complete response, SD stable disease, PR partial response, BMI body mass index