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Table 1 Demographic and clinical characteristics associated with POD in elderly GC patients

From: Risk factors and a nomogram model for postoperative delirium in elderly gastric cancer patients after laparoscopic gastrectomy

 

POD

 

Variables

No (n = 196)

Yes (n = 74)

p-value

Age (year)

72.5 ± 3.8

75.8 ± 3.8

< 0.001*

BMI (kg/m2)

20.8 ± 2.3

21.0 ± 2.5

0.534

Gender, n (%)

-

-

0.524

 Male

127 (64.8)

51 (68.9)

-

 Female

69 (35.2)

23 (31.1)

-

ASA physical status, n (%)

-

-

0.023*

 I-II

158 (80.6)

50 (67.6)

-

 III-IV

38 (19.4)

24 (32.4)

-

Smoking, n (%)

37 (18.9)

15 (20.3)

0.796

Drinking, n (%)

30 (15.3)

19 (25.7)

0.049*

Education level, n (%)

-

-

0.218

 ≥ High school

33 (16.8)

8 (10.8)

-

 < High school

163 (83.2)

66 (89.2)

-

History of abdominal surgery, n (%)

47 (24.0)

21 (28.4)

0.458

Preoperative medications, n (%)

-

-

-

 Antidiabetics

26 (13.3)

10 (13.5)

0.957

 Antihypertensive drugs

38 (19.4)

12 (16.2)

0.550

 Sleeping pills

19 (9.7)

16 (21.6)

0.009*

Preoperative anxiety, n (%)

25 (12.8)

18 (24.3)

0.021*

ECOG status, n (%)

-

-

0.094

 0

140 (71.4)

45 (60.8)

-

 ≥ 1

56 (28.6)

29 (39.2)

-

Types of surgery, n (%)

-

-

0.560

 Total gastrectomy

59 (30.1)

25 (33.8)

-

 Partial gastrectomy

137 (69.9)

49 (66.2)

-

Operation time (h)

2.8 ± 0.6

3.0 ± 0.5

0.011*

Time to awakening (min)

38.2 ± 6.5

40.1 ± 7.3

0.039*

Estimated blood loss (ml)

150 (85)

160 (90)

0.172

Surgical APGAR score

6.2 ± 1.4

5.9 ± 1.5

0.125

Tumor location, n (%)

-

-

0.644

 Upper 1/3

23 (11.7)

9 (12.2)

-

 Middle 1/3

70 (35.7)

22 (29.7)

-

 Low 1/3

103 (52.6)

43 (58.1)

-

Lymph node dissection

-

-

0.697

 D0-D1

119 (60.7)

43 (58.1)

-

 ≥ D2

77 (39.3)

31 (41.9)

-

Pathological TNM stage

-

-

0.517

 II

116 (59.2)

47 (63.5)

-

 III

80 (40.8)

27 (36.5)

-

Duration of ICU stay (d)

1.8 ± 0.9

2.2 ± 1.0

0.002*

Duration of hospital stay (d)

11.8 ± 2.2

12.7 ± 2.4

0.004*

  1. POD postoperative delirium, GC gastric cancer, BMI body mass index, ASA American Society of Anesthesiologists, ECOG Eastern Cooperative Oncology Group, ICU intensive care unit
  2. *P-value < 0.05 by chi-square test, Fisher exact test, t-test, or Mann-Whitney U-test