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Table 5 Comparison of single and combined MDCT, CA199, CA242, and CEA in diagnosis of PC

From: Value of multi-detector computed tomography combined with serum tumor markers in diagnosis, preoperative, and prognostic evaluation of pancreatic cancer

Index

Sensitivity

Specificity

Accuracy

Positive predictive value

Negative predictive value

MDCT

81.18(69/85)

87.18(34/39)

83.06(103/124)

92.86(69/71)

68.18(34/50)

CA199

71.76 (61/85)

84.61(33/39)

75.81(94/124)

91.04(61/67)

57.89(33/57)

CA242

68.24(58/85)

89.74(35/39)

75.00(93/124)

93.55(58/62)

56.45(35/62)

CEA

64.71(55/85)

87.18()34/39)

71.77(89/124)

91.67(55/60)

53.13(34/64)

Combined detection

96.47(82/85)a,b,c,d

82.05(32/39)

91.94(114/124)a,b,c,d

92.13(82/89)

94.12(32/34)a,b,c,d

χ2

35.791

1.118

19.864

0.415

17.056

    

0.981

 
  1. ap < 0.01, compared with MDCT group; bp < 0.01, compared with CA199 group, cp < 0.01, compared with CA242 group. dp < 0.01, compared with CEA group