Table 1 Baseline characteristics of included studies in this meta-analysis
Study | Year | Country | Study period | Study design | Sample size | Age (years) Median (range) | Sex (M/F) | Histology | TNM stage | Treatment | Follow-up (months) Median (range) | Cut-off value of SII | Survival endpoints | Survival analysis | NOS score |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ha, H. | 2016 | Korea | 2004–2009 | Retrospective | 158 | 59.6 (31.3–76.2) | 103/55 | BTC | IV | Chemotherapy | 95.3 | 572.38 | OS | Multivariate | 7 |
Hu, X. | 2019 | China | 2012–2017 | Retrospective | 113 | 70 | 75/38 | ECC | I–IV | PTBS + 125I | To Sep 2017 | 456 | OS | Univariate | 7 |
Sellers, C. M. | 2019 | USA | 2005–2016 | Retrospective | 131 | 65 (57–71) | 68/63 | ICC | I–IV | Surgery | 12 | 867 | OS | Univariate | 8 |
Li, H. | 2020 | China | 2009–2017 | Retrospective | 530 | 57.2 | 256/274 | ICC | I–III | Surgery | 18.0 (1.0-115.4) | 450 | OS, RFS | Multivariate | 7 |
Sun, L. | 2020 | China | 2003–2017 | Retrospective | 142 | 63 | 60/82 | GBC | I–IV | Surgery | 12 | 600 | OS | Multivariate | 8 |
Tsilimigras, D. I. | 2020 | USA | 2000–2017 | Retrospective | 688 | 57 (49–65) | 416/272 | ICC | I–III | Surgery | 22.3 | 1,150 | OS, RFS | Multivariate | 8 |
Zhang, Z. | 2020 | China | 2013–2017 | Retrospective | 128 | 56.19 | 70/58 | ICC | I–III | Surgery | 25.2 | 1,027 | OS, RFS | Multivariate | 7 |
Chen, H. | 2021 | China | 2012–2020 | Retrospective | 93 | 62 (32–90) | 62/31 | GBC | I–III | Surgery | 14 (2-60) | 824 | OS | Multivariate | 8 |
Du, F. | 2021 | China | 2016–2019 | Retrospective | 60 | 61 (28–83) | 41/19 | BTC | IV | Immunotherapy | To Apr 2020 | 710 | OS, PFS | Univariate | 6 |
Li, L. | 2021 | China | 2002–2019 | Retrospective | 1072 | 62 | 414/658 | GBC | I–III | Surgery | 53.8 | 510 | OS | Multivariate | 7 |
Ren, A. | 2021 | China | 2013–2018 | Retrospective | 28 | 51.5 (46.8–60) | 25/3 | ICC | IV | Liver transplantation | 33.5 | 447.48 | OS, RFS | Multivariate | 8 |
Terasaki, F. | 2021 | Japan | 2002–2015 | Retrospective | 140 | 71 (39–85) | 109/31 | ECC | I–III | Surgery | 48.2 | 1,450 | OS | Multivariate | 8 |
Di Martino, M. | 2022 | Italy | 2010–2019 | Retrospective | 232 | 70 | 146/86 | ECC | I–IV | Surgery | 35.8 | 592 | OS, RFS | Univariate | 7 |