Stereotactic body radiotherapy for recurrent and oligometastatic soft tissue sarcoma

Table 3 Univariate analysis for OS, PFS, and LC

	OS		PFS		LC
	HR 95% CI	p	HR 95% CI	p	HR 95% CI	p
Disease setting	0.363	0.016	0.280	0.003	0.692	0.495
Recurrence VS oligometastasis	0.159–0.828		0.123–0.641		0.240–1.993
Histological grade	0.183	0.0001	0.179	0.0001	0.210	0.0094
G1 vs G2 and G3	0.077–0.432		0.074–0.431		0.065–0.682
Number of lesions^a	0.335	0.028	0.268	0.009	0.308	0.056
1 vs 2–3	0.126–0.887		0.099–0.720		0.092–1.030
Lesions size	0.745	0.483	0.822	0.638	0.282	0.013
≤ 5 cm vs > 5 cm	0.327–1.697		0.362–1.863		0.104–0.763
BED	0.629	0.248	0.597	0.206	0.595	0.324
< 100 Gy vs ≥ 100 Gy	0.278–1.381		0.269–1.327		0.212–1.671

Abbreviations:LC local control, PFS progression-free survival, OS overall survival, BED biologically equivalent dose
^aNumber of concurrent lesions at the time of first SBRT