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Table 1 Clinicopathologic characteristics between negative and positive LN metastasis groups

From: Risks and benefits of additional surgery for early gastric cancer in the upper third of the stomach meeting non-curative resection criteria after endoscopic submucosal dissection

Variables

Negative LNM group

[n = 343 (%)]

Positive LNM group

[n = 36 (%)]

P value

Age (mean ± SD) (year)

58.5 ± 11.1

58.5 ± 14.2

0.995

Sex

0.08

 Male

250 (72.9)

21 (58.3)

 Female

93 (27.1)

15 (41.7)

BMI

24.1 ± 2.8

23.7 ± 3.2

0.363

ASA

0.459

 1

127 (37.1)

11 (30.6)

 2

193 (56.4)

24 (66.7)

 3

22 (6.4)

1 (2.8)

Approach

0.132

 Open

153 (44.6)

22 (61.1)

 Laparoscopic

166 (48.4)

13 (36.1)

 Robot

24 (7.0)

1 (2.8)

Extent of gastrectomy

0.826

 Total

277 (80.8)

30 (83.3)

 Proximal

66 (19.2)

6 (16.7)

Tumor size (mean ± SD) (cm)

3.5 ± 1.6

3.7 ± 2.0

0.549

Tumor size

0.861

  ≤ 3 cm

154 (44.9)

17 (47.2)

  > 3 cm

189 (55.1)

19 (52.8)

Histology

0.152

 Differentiated

134 (39.1)

19 (52.8)

 Undifferentiated

209 (60.9)

17 (47.2)

Depth of invasion

0.011

 Mucosa

87 (25.4)

2 (5.6)

 SM1 (< 500 μm)

35 (10.2)

2 (5.6)

 SM2 (≥ 500 μm)

221 (64.4)

32 (88.9)

Ulcer

0.507

 Absent

275 (80.2)

31 (86.1)

 Present

68 (19.5)

5 (13.9)

LVI

 < 0.001

 Absent

300 (87.5)

17 (47.2)

 Present

43 (12.5)

19 (52.8)

  1. LNM Lymph node metastasis, BMI Body mass index, ASA American Society of Anesthesiologists, SM Submucosa, LVI Lymphovascular invasion