Variables | Univariate | P | Multivariate | P | ||
---|---|---|---|---|---|---|
HR | 95% CI | HR | 95% CI | |||
Age, years | 0.059 | 0.128 | ||||
< 65 | Reference | Reference | ||||
≥ 65 | 1.278 | 0.990–1.650 | 1.223 | 0.944–1.586 | ||
Gender | 0.852 | |||||
Female | Reference | |||||
Male | 0.974 | 0.740–1.282 | ||||
Postoperative morbidity | 0.267 | |||||
No | Reference | |||||
Yes | 0.734 | 0.419–1.275 | ||||
BMI, kg/m2 | 0.040 | 0.059 | ||||
≥ 25 | Reference | Reference | ||||
< 25 | 1.520 | 1.018–2.267 | 1.591 | 1.049–2.414 | ||
ASA score | 0.435 | |||||
0–1 | Reference | |||||
≥ 2 | 1.056 | 0.382–2.912 | ||||
Histology type | 0.121 | |||||
Well/moderately | Reference | |||||
Poorly/undifferentiated | 1.415 | 1.078–1.862 | ||||
Tumor size, cm | 0.043 | 0.751 | ||||
< 4 | Reference | Reference | ||||
≥ 4 | 1.299 | 1.009–1.674 | 0.958 | 0.737–1.246 | ||
Pathologic T stage | 0.000 | 0.019 | ||||
T2 | Reference | |||||
T3-T4a | 3.332 | 1.805–6.149 | 3.429 | 1.229–9.568 | ||
Pathologic N stage | 0.000 | 0.032 | ||||
N negative | Reference | |||||
N positive | 2.985 | 2.080–4.283 | 2.370 | 1.075–5.225 | ||
Pathologic TNM stage | 0.000 | 0.024 | ||||
IB | Reference | Reference | ||||
IIA-IIIC | 4.016 | 2.113–7.635 | 3.812 | 1.445–14.325 | ||
Surgical procedure | 0.710 | |||||
RADG | Reference | |||||
LADG | 0.953 | 0.741–1.227 |