Variables | Univariate | P | Multivariate | P | ||
---|---|---|---|---|---|---|
HR | 95% CI | HR | 95% CI | |||
Age, years | 0.036 | 0.065 | ||||
< 65 | Reference | Reference | ||||
≥ 65 | 1.324 | 1.018–1.721 | 1.285 | 0.985–1.676 | ||
Gender | 0.966 | |||||
Female | Reference | |||||
Male | 1.006 | 0.759–1.333 | ||||
Postoperative morbidity | 0.321 | |||||
No | Reference | |||||
Yes | 0.785 | 0.432–1.325 | ||||
BMI, kg/m2 | 0.070 | 0.064 | ||||
< 25 | Reference | Reference | ||||
≥ 25 | 0.686 | 0.456–1.032 | 0.670 | 0.438–1.024 | ||
ASA score | 0.912 | |||||
0–1 | Reference | |||||
≥ 2 | 1.056 | 0.382–2.912 | ||||
Histology type | 0.146 | |||||
Well/moderately | Reference | |||||
Poorly/undifferentiated | 1.378 | 0.890–2.140 | ||||
Tumor size, cm | 0.049 | 0.917 | ||||
< 4 | Reference | Reference | ||||
≥ 4 | 1.300 | 1.002–1.688 | 0.986 | 0.752–1.292 | ||
Pathologic T stage | 0.001 | 0.011 | ||||
T2 | Reference | |||||
T3-T4a | 2.863 | 1.538–5.327 | 3.316 | 1.319–8.342 | ||
Pathologic N stage | 0.028 | 0.042 | ||||
N negative | Reference | |||||
N positive | 2.350 | 1.095–5.042 | 2.458 | 1.338–5.922 | ||
Pathologic TNM stage | 0.000 | 0.012 | ||||
IB | Reference | Reference | ||||
IIA-IIIC | 3.709 | 1.945–7.076 | 3.804 | 1.420–15.249 | ||
Surgical procedure | 0.521 | |||||
RADG | Reference | |||||
LADG | 0.918 | 0.707–1.192 |