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Fig. 8 | World Journal of Surgical Oncology

Fig. 8

From: Circ_0000808 promotes the development of non-small cell lung cancer by regulating glutamine metabolism via the miR-1827/SLC1A5 axis

Fig. 8

Downregulated circ_0000808 reduced NSCLC tumorigenesis. NCI-H1299 cells transfected with sh-NC or sh-circ_0000808 were injected into nude mice. A Images of tumors in each group. B Tumor volume was measured every 7 days. C Tumor weight was detected after 35 days. D The expression of circ_0000808, miR-1827, and SLC1A5 in the tumor tissues of each group was determined by qRT-PCR. E The protein expression of SLC1A5 in the tumor tissues of each group was examined by WB analysis. F IHC staining was used to assess the positive cells of SLC1A5, ki67, Bax, and E-cadherin in the tumor tissues of each group. ***P < 0.001

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