Fig. 2

Effects of sh-circ_0000808 on NSCLC cell proliferation, apoptosis, migration, and invasion. A549 and NCI-H1299 cells were transfected with sh-NC or sh-circ_0000808. A The expression of circ_0000808 was measured by qRT-PCR. CCK8 assay (B–C), colony formation assay (D), and EdU staining (E) were performed to assess cell proliferation. Flow cytometry (F), wound healing assay (G), and transwell assay (H-I) were used to examine cell apoptosis, migration, and invasion (J–K). The protein levels of ki67, Bax, and E-cadherin were determined by WB analysis. **P < 0.01, ***P < 0.001