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Table 2 Risk factors for DFS and OS by univariate analysis

From: Preoperative low absolute lymphocyte count to fibrinogen ratio correlated with poor survival in nonmetastatic colorectal cancer

 

DFS

OS

P

HR

95% CI

P

HR

95% CI

Age (years)

 < 60

1

  

1

  

 ≥ 60

0.56

1.17

0.69–1.95

0.02*

2.17

1.14–4.16

Gender

 Male

1

  

1

  

 Female

0.03*

0.53

0.30–0.95

0.03*

0.46

0.23–0.93

Tobacco use history

 Never

1

  

1

  

 Current + former

0.93

1.02

0.59–1.77

0.80

1.09

0.57–2.08

Alcohol use history

 Never

1

  

1

  

 Current + former

0.11

1.52

0.91–2.53

0.25

1.42

0.78–2.57

Hypertension

 Without

1

  

1

  

 With

0.94

1.03

0.54–1.93

0.42

1.33

0.67–2.62

Type 2 diabetes

 Without

1

  

1

  

 With

0.34

1.65

0.60–4.55

0.78

1.16

0.41–3.23

Tumor sites

 Right

1

  

1

  

 Left

0.36

0.75

0.41–1.39

0.34

0.70

0.34–1.45

Histological grade

 Well + moderate

1

  

1

  

 Poor

0.13

1.63

0.87–3.08

0.03*

2.12

1.07–4.20

Mucinous constituent

      

 Without

1

  

1

  

 With

0.60

1.19

0.62–2.30

0.41

1.37

0.66–2.84

Tumor deposits

 Without

1

  

1

  

 With

< 0.01*

5.60

2.98–10.55

< 0.01*

7.51

3.77–14.94

CEA level

 Normal

1

  

1

  

 Elevated

< 0.01*

2.22

1.33–3.70

< 0.01*

3.01

1.65–5.49

CA19-9 level

 Normal

1

  

1

  

 Elevated

0.01*

2.15

1.18–3.92

< 0.01*

3.17

1.68–5.98

Combined T stages

 T1 + T2

1

  

1

  

 T3 + T4

< 0.01*

3.22

1.46–7.09

0.01*

4.08

1.46–11.40

Combined N stages

 N0

1

  

1

  

 N1 + N2

< 0.01*

2.60

1.55–4.36

< 0.01*

2.50

1.37–4.56

TNM stages

 I

1

  

1

  

 II

0.09

2.35

0.88–6.23

0.04*

4.73

1.09–20.49

 III

< 0.01*

4.56

1.78–11.68

0.01*

7.97

1.89–33.65

BMI (kg/m2)

0.01*

0.90

0.84–0.98

0.01*

0.89

0.82–0.98

LFR

 Low

1

  

1

  

 High

< 0.01*

0.27

0.14–0.51

< 0.01*

0.17

0.07–0.41

  1. *With significant statistical difference