Table 3 Univariate Cox regression analysis of OS and DFS for all included patients

Age (≤ 50 y vs. > 50 y)

1.502

0.623–3.624

0.365

1.563

0.716–3.413

0.263

Menopausal state (premenopausal vs Postmenopausal)

0.781

0.342–1.884

0.582

0.887

0.412–1.912

0.760

Tumor size (≤ 2 cm vs > 2 cm)

4.148

1.395–12.330

0.010*

3.452

1.393–8.557

0.007*

Histological grade (G1, G2, or G3)

2.020

0.784–5.208

0.145

1.812

0.766–4.285

0.176

TNM stage (I, II, vs III)

2.658

1.101–6.414

0.030*

2.195

0.986–4.887

0.054

Cancer thrombus (no vs yes)

2.505

0.972–6.457

0.057

1.829

0.738–4.533

0.192

Lymph node metastasis (no vs yes)

3.390

1.315–8.742

0.012*

2.351

1.076–5.136

0.032*

Estrogen receptor (negative vs positive)

0.342

0.145–0.806

0.014*

0.401

0.187–0.856

0.018*

Progesterone receptor (negative vs positive)

0.443

0.172–0.142

0.092

0.671

0.307–1.465

0.317

HER-2 (negative vs positive)

2.016

1.283–3.168

0.002*

1.977

1.328–2.943

0.001*

Ki-67 (low vs high)

2.105

0.708–6.257

0.180

2.146

0.812–5.666

0.123

PBK/TOPK (low vs high)

4.590

1.681–12.530

0.003*

2.890

1.298–6.433

0.009*

Chemotherapy (yes vs no)

2.003

0.268–15.018

0.498

2.669

0.361–19.728

0.336