Parameter | Total, N (%) | PBK/TOPK | |||
---|---|---|---|---|---|
(n = 202) | Low, N (%) | High, N (%) | rs | P | |
Age | |||||
≤ 50 y | 94 (46.5) | 52 (55.3) | 42 (44.7) | −0.049 | 0.487 |
> 50 y | 108 (53.5) | 65 (60.2) | 43 (39.8) | ||
Menopausal state | |||||
Premenopausal | 115 (56.9) | 63 (54.8) | 52 (45.2) | −0.073 | 0.301 |
Postmenopausal | 87(43.1) | 54 (62.1) | 33 (37.9) | ||
Tumor size | |||||
≤ 2 cm | 95 (47.0) | 61 (64.2) | 34 (35.8) | ||
> 2 cm ≤ 5 cm | 96 (47.6) | 51 (53.1) | 45 (46.9) | 0.124 | 0.078 |
> 5 cm | 11 (5.4) | 5 (45.5) | 6 (54.5) | ||
Histological | |||||
G1 | 20 (9.9) | 13 (65.0) | 7 (35.0) | ||
G2 | 147 (72.8) | 93 (63.3) | 54 (36.7) | 0.171 | 0.015* |
G3 | 35 (17.3) | 11 (31.4) | 24 (68.6) | ||
TNM | |||||
I | 66 (32.7) | 45 (68.2) | 21 (31.8) | ||
II | 95 (47.0) | 54 (56.8) | 41 (43.2) | 0.175 | 0.013* |
III | 41 (20.3) | 18 (43.9) | 23 (56.1) | ||
Cancer thrombus | |||||
No | 172 (85.1) | 103 (59.9) | 69 (40.1) | 0.095 | 0.178 |
Yes | 30 (14.9) | 14 (46.7) | 16 (53.3) | ||
Lymph node metastasis | |||||
No | 113 (55.9) | 76 (67.2) | 37 (32.8) | 0.213 | 0.002* |
Yes | 89 (44.1) | 41 (46.1) | 48 (53.9) | ||
Number of lymph nodes | |||||
1–3 | 56 (27.7) | 29 (51.8) | 27 (48.2) | ||
4–9 | 20 (9.9) | 10 (50.0) | 10 (50.0) | 0.241 | 0.001* |
≥ 10 | 13 (6.5) | 2 (15.4) | 11 (84.6) | ||
Estrogen receptor | |||||
Negative | 53 (26.2) | 22 (41.5) | 31 (58.5) | −0.198 | 0.005* |
Positive | 149 (73.8) | 95 (63.8) | 54 (36.2) | ||
Progesterone receptor | |||||
Negative | 110 (54.5) | 56 (50.9) | 54 (49.1) | −0.155 | 0.027* |
Positive | 92 (45.5) | 61 (66.3) | 31 (33.7) | ||
HER-2 | |||||
Negative | 137 (67.8) | 85 (62.0) | 52 (38.0) | 0.153 | 0.037* |
Positive | 49 (24.2) | 22 (44.9) | 27 (55.1) | ||
Ki-67 | |||||
Low expression | 65 (32.2) | 52 (80.0) | 13 (20.0) | 0.312 | < 0.001* |
High expression | 137 (67.8) | 64 (46.7) | 73 (53.3) | ||
Molecular typing | |||||
Luminal A | 33 (16.3) | 30 (90.9) | 3 (9.1) | 22.031^ | < 0.001^ |
Luminal B | 74 (36.6) | 43 (58.1) | 31 (41.9) | ||
HER-2(+) | 49 (24.2) | 22 (44.9) | 27 (55.1) | ||
TNBC | 30 (14.9) | 12 (40.0) | 18 (60.0) |