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Table 4 GO and KEGG enrichment analyses of STMN1 and functional partner genes in HCC

From: STMN1 as a novel prognostic biomarker in HCC correlating with immune infiltrates and methylation

Ontology

ID

Description

p-value

BP

GO:0010389

Regulation of G2/M transition of mitotic cell cycle

2.93e-08

BP

GO:1901990

Regulation of mitotic cell cycle phase transition

3.39e-08

BP

GO:0000086

G2/M transition of mitotic cell cycle

9.29e-08

BP

GO:0007093

Mitotic cell cycle checkpoint

1.19e-06

BP

GO:1903580

Positive regulation of ATP metabolic process

1.77e-06

BP

GO:0006977

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

3.02e-06

BP

GO:1901991

Negative regulation of mitotic cell cycle phase transition

5.99e-06

BP

GO:0018105

Peptidyl-serine phosphorylation

1.25e-05

CC

GO:0005874

Microtubule

9.43e-07

CC

GO:0000780

Condensed nuclear chromosome, centromeric region

7.48e-05

MF

GO:0035173

Histone kinase activity

8.80e-08

MF

GO:0005200

Structural constituent of cytoskeleton

2.17e-05

MF

GO:0004674

Protein serine/threonine kinase activity

6.97e-05

MF

GO:0004683

Calmodulin-dependent protein kinase activity

1.08e-04

KEGG

hsa04540

Gap junction

1.59e-06

KEGG

hsa04110

Cell cycle

2.77e-04

KEGG

hsa04068

FoxO signaling pathway

3.26e-04

KEGG

hsa04210

Apoptosis

3.64e-04

KEGG

hsa04145

Phagosome

5.05e-04

KEGG

hsa04530

Tight junction

6.89e-04

KEGG

hsa05130

Pathogenic Escherichia coli infection

0.001

KEGG

hsa05203

Viral carcinogenesis

0.001

KEGG

hsa05206

MicroRNAs in cancer

0.044