Table 1 Clinical features associated with overall survival by univariate and multivariate cox regression analysis

Age (< = 60 vs. > 60)

373

1.205 (0.850–1.708)

0.295

1.327 (0.811–2.170)

0.260

Tumor status

354

2.317 (1.590–3.376)

< 0.001

1.883 (1.105–3.210)

0.020

T stage (T1 & T2 vs. T3 & T4)

370

2.598 (1.826–3.697)

< 0.001

2.728 (0.153–48.666)

0.495

N stage (N0 vs. N1)

258

2.029 (0.497–8.281)

0.324

2.721 (0.355–20.857)

0.335

M stage (M0 vs. M1)

272

4.077 (1.281–12.973)

0.017

1.874 (0.410–8.572)

0.418

Pathologic stage (stage 1 & stage 2 vs. stage 3 & stage IV)

349

2.504 (1.727–3.631)

< 0.001

0.882 (0.049–16.023)

0.933

Histologic grade (G1 & G2 vs. G3 & G4)

368

1.091 (0.761–1.564)

0.636

1.092 (0.669–1.782)

0.726

STMN1 (low vs. high)

373

1.785 (1.256–2.536)

0.001

2.009 (1.164–3.466)

0.012