Table 6 The univariate and multivariate Cox proportional hazard regression for screening prognostic factors for HCC overall survival

Older age

0.01

1.03 (1.02–1.05)

0.01

1.03 (1.01–1.06)

Sex (male)

0.18

0.6 (0.4–1.18)

Viral etiology

0.94

0.9 (0.4– 2.1)

 IFN

0.57

1.2 (0.6–2.0)

 DAAs

0.28

0.7 (0.3–1.3)

Serum AFP

0.64

1.0 (1.0–1.0)

Tumor focality (multiple)

0.21

1.3 (0.8–1.9)

Tumor size

0.01

1.1 (1.017–1.2)

0.007

1.1 (1.02–1.2)

 I

Reference

 II

0.91

0.9 (0.4–1.8)

 III

0.46

1.3 (0.6–2.8)

 0–10

Reference

 20–40

0.03

0.4 (0.2–0.9)

0.006

0.3 (0.2–0.7)

 Absent

Reference

 Present

0.01

1.6 (1.1–2.4)

0.002

1.9 (1.2–2.8)

 Dominant

0.01

2.9 (1.2–6.8)

0.02

2.8 (1.2-6.6)

 1

Reference

 2

0.66

1.3 (0.3–5.7)

 3

0.53

1.6 (0.3–7.2)

 4

0.30

2.5 (0.4–15.5)

Tumor stage (late)

0.25

1.4 (0.7–2.5)

Liver cirrhosis

0.22

1.2 (0.8–1.9)

LVI

0.27

1.2 (0.8–2.1)