Fig. 3

Microscopic aspects of HCC, NOS. a A well differentiated HCC showed thin trabaecule (IHC, 100×). b A moderately differentiated HCC showed wide acini filled with eosinophilic to bile secretion (IHC, 100×). c A moderately differentiated HCC showed mixed acinar and trabecular pattern (IHC, 100×). d A poorly differentiated HCC showed solid pattern with marked nuclear atypia (IHC, 100×). e HCC, NOS with mild intra-tumoral lymphocytes (IHC, 100×). f HCC, NOS with hemangiopericytoma like pattern (IHC, 100×). g HCC, NOS with prominent osteoclast like giant cells (IHC, 100×). h HCC with prominent lymphovascular invasion (arrows) (IHC, 100×). i HCC with bile duct invasion with attached tumor emboli to the epithelial cells (arrows) (IHC, 100×). j HCC with perineural invasion (arrows) (IHC, 100×). k HCC, NOS associated with calcified bilharzial ova (arrows) (IHC, 100×)