Table 4 The potential risk factors for up-staging
From: Surgical staging of apparent early-stage ovarian mucinous carcinoma
Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
P-value | OR (95%CI) | P-value | OR (95%CI) | |
Age | 0.973 | 1.001 (0.960–1.043) | ||
Body mass index | 0.468 | 0.934 (0.778–1.123) | ||
Multipara | 0.288 | 1.819 (0.604–5.480) | ||
During the pregnancy | 0.209 | 3.046 (0.535–17.334) | ||
A history of ovarian mucinous tumor | 0.033 | 4.364 (1.128–16.878) | 0.033 | 4.745 (1.132–19.886) |
CEA elevated at the time of diagnosis | 0.772 | 1.429 (0.129–15.875) | ||
CA199 elevated at the time of diagnosis | 0.419 | 1.884 (0.405–8.765) | ||
CA125 elevated at the time of diagnosis | 0.343 | 1.979 (0.483–8.111) | ||
Laparoscopy at first-step surgery | 0.791 | 1.200 (0.312–4.622) | ||
Ovarian cystectomy | 0.350 | 1.750 (0.541–5.658) | ||
Ascites | 0.326 | 1.921 (0.522–7.063) | ||
Tumor size | 0.153 | 1.057 (0.979–1.142) | ||
Bilateral ovary involvement | 0.005 | 8.909 (1.949–40.718) | 0.005 | 9.739 (2.016–47.056) |
One-step staging surgery | 0.511 | 0.682 (0.218–2.136) | ||
Time interval between surgeries | 0.186 | 1.004 (0.998–1.010) | ||
With malignant mural nodules | 0.308 | 3.607 (0.307–42.419) | ||
Expansile subtype tumor | 0.943 | 0.948 (0.220–4.096) | ||
Poorly differentiated tumor | 0.417 | 0.418 (0.051–3.439) | ||