Skip to main content
Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: Prognostic value of functional SMAD4 localization in extrahepatic bile duct cancer

Fig. 2

The definition of tumor invasion front and tumor central lesion, and typical immunohistochemical labeling for SMAD4 in extrahepatic biliary tract cancer. a The definition of tumor invasion front and tumor central lesion. Scale bar = 500 µm, × 20 magnification. be Typical immunohistochemical labeling for SMAD4 in extrahepatic biliary tract cancer. Scale bar = 50 µm, × 400 magnification. b Nuclear SMAD4 expression is negative, score = 0. c The percentage of nuclear positive SMAD4 is 0–25%, score = 1. d The percentage of nuclear positive SMAD4 is 25–50%, score = 2. e The percentage of nuclear positive SMAD4 is above 50%, score = 3

Back to article page