Fig. 4From: A progressive and refractory case of breast cancer with Cowden syndromePostoperative pathological examinations of the right breast after chemotherapy (× 200 magnification). H&E staining shows remains of invasive ductal carcinoma (a). ER staining was negative (b). HER2 staining was negative (c). Ki67 labeling index was 90% (d). Black bar represents 100 μm length. Therapeutic effect of chemotherapy was grade 1aBack to article page