Table 2 Univariate and Cox model analyses of patients’ clinical parameters and METTL3 expression in PC tissues

Gender (male:female)

1.126 (0.690 ~ 1.839)

0.635

1.031 (0.592 ~ 1.796)

0.914

Age (≥ 60 years: < 60 years)

1.222 (0.759 ~ 1.968)

0.410

1.836 (1.090 ~ 3.094)

0.022

Tumor diameter (≥ 4 cm: < 4 cm)

0.877 (0.541 ~ 1.422)

0.595

0.685 (0.407 ~ 1.152)

0.153

TNM stages (II + III + IV: I)

1.912 (1.149 ~ 3.181)

0.013

2.407 (1.392 ~ 4.162)

0.002

Distance metastasis (yes:no)

1.746 (0.426 ~ 7.162)

0.439

0.706 (0.151 ~ 3.313)

0.659

Vascular invasion (yes:no)

1.336 (0.825 ~ 2.160)

0.238

1.080 (0.649 ~ 1.798)

0.767

Pathological stage (G3 + G4:G2)

1.852 (1.127 ~ 3.043)

0.015

2.271 (1.287 ~ 4.006)

0.005

METTL3 (high:low)

1.788 (1.071 ~ 2.984)

0.026

2.243 (1.309 ~ 3.843)

0.003