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Table 2 Univariate and Cox model analyses of patients’ clinical parameters and METTL3 expression in PC tissues

From: Increased expression of METTL3 in pancreatic cancer tissues associates with poor survival of the patients

Characteristics Univariate analysis Multivariate analysis
HR (95% CI) P HR (95% CI) P
Gender (male:female) 1.126 (0.690 ~ 1.839) 0.635 1.031 (0.592 ~ 1.796) 0.914
Age (≥ 60 years: < 60 years) 1.222 (0.759 ~ 1.968) 0.410 1.836 (1.090 ~ 3.094) 0.022
Tumor diameter (≥ 4 cm: < 4 cm) 0.877 (0.541 ~ 1.422) 0.595 0.685 (0.407 ~ 1.152) 0.153
TNM stages (II + III + IV: I) 1.912 (1.149 ~ 3.181) 0.013 2.407 (1.392 ~ 4.162) 0.002
Distance metastasis (yes:no) 1.746 (0.426 ~ 7.162) 0.439 0.706 (0.151 ~ 3.313) 0.659
Vascular invasion (yes:no) 1.336 (0.825 ~ 2.160) 0.238 1.080 (0.649 ~ 1.798) 0.767
Pathological stage (G3 + G4:G2) 1.852 (1.127 ~ 3.043) 0.015 2.271 (1.287 ~ 4.006) 0.005
METTL3 (high:low) 1.788 (1.071 ~ 2.984) 0.026 2.243 (1.309 ~ 3.843) 0.003
  1. Bold signifies P < 0.05