Table 2 Clinical characteristics of stage III colon cancer patients by adjuvant chemotherapy
Variables | Adjuvant chemotherapy | p-value | Total (n = 690) | |
|---|---|---|---|---|
Yes (n = 434) | No (n = 256) | |||
Hospital length of stay, days | ||||
Median (IQR) | 7 (5–9) | 8 (6–13) | < 0.01 | 7 (5–10) |
Mean (SD) | 8.0 (5.1) | 10.2 (6.8) | < 0.01 | 9 (6) |
Age, median (min-max) | 65 (19–83) | 81 (41–93) | < 0.01 | 71 (19–93) |
Gender,n(%) | ||||
Female | 221 (51) | 154 (60) | < 0.05 | 375 (54) |
Male | 213 (49) | 102 (40) | 315 (46) | |
Surgery,n(%) | ||||
Open | 368 (85) | 217 (85) | NS | 585 (85) |
Laparoscopic | 66 (15) | 39 (15) | 105 (15) | |
Tumor location,n(%)a | ||||
Right sided | 216 (50) | 152 (59) | NS | 368 (53) |
Left sided | 212 (49) | 101 (39) | 313 (45) | |
Multiple locations | 6 (1) | 3 (1) | 9 (1) | |
Differentiation grade,n(%) | ||||
Low grade (G1–G2) | 308 (71) | 175 (68) | NS | 483 (70) |
High grade (G3–G4) | 105 (24) | 63 (25) | 168 (24) | |
Mucinous | 21 (5) | 18 (7) | 39 (6) | |
Number of positive lymph nodes, median (IQR) | 3 (1–5) | 2 (1–4) | < 0.01 | 2 (1–5) |
T-stage,n(%) | ||||
1 | 8 (2) | 2 (1) | < 0.05 | 10 (1) |
2 | 28 (6) | 16 (6) | 44 (6) | |
3 | 291 (67) | 196 (77) | 487 (71) | |
4 | 107 (25) | 42 (16) | 149 (22) | |
N-stage,n(%) | ||||
N1 | 268 (62) | 178 (70) | < 0.05 | 446 (65) |
N2 | 166 (38) | 78 (30) | 244 (35) | |
ACCI,n(%)a | ||||
0–2 | 250 (58) | 12 (5) | < 0.01 | 262 (38) |
3–5 | 176 (41) | 200 (78) | 376 (54) | |
6–9 | 8 (2) | 44 (17) | 52 (8) | |
Clavien-Dindo,n(%) | ||||
0–3a | 407 (94) | 237 (93) | NS | 644 (93) |
3b–4 | 27 (6) | 19 (7) | 46 (7) | |
Readmission,n(%) | ||||
No | 403 (93) | 240 (94) | NS | 643 (93) |
Yes | 31 (7) | 16 (6) | 47 (7) | |