Table 3 Uni- and multivariate predictive factors of POPF after DP
n | Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p-value | OR | 95% CI | p-value | |||
Preoperative | Age (years) | |||||||
>70 | 45 | 0.79 | 0.32–1.89 | 0.61 | ||||
<70 | 72 | 1 | ||||||
Sex | ||||||||
Male | 68 | 1.24 | 0.53–3.01 | 0.62 | ||||
Female | 49 | 1 | ||||||
BMI (kg/m2) | ||||||||
>24 | 39 | 2.07 | 0.85–5.00 | 0.10 | ||||
<24 | 77 | 1 | ||||||
Pancreatic ductal adenocarcinoma | ||||||||
Yes | 55 | 0.74 | 0.31–1.72 | 0.48 | ||||
No | 62 | 1 | ||||||
Location | ||||||||
Body | 68 | 0.59 | 0.25–1.37 | 0.22 | ||||
Tail | 49 | 1 | ||||||
Pancreas-to-muscle SIR on T1-w MRI | ||||||||
>1.37 | 61 | 29.7 | 5.83–543.73 | <0.01✝ | 23.25 | 3.93–454.03 | <0.01✝ | |
<1.37 | 41 | 1 | 1 | |||||
Intraoperative | Operative time (min) | |||||||
>300 | 38 | 1.36 | 0.55–3.24 | 0.50 | ||||
<300 | 78 | 1 | ||||||
Blood loss (ml) | ||||||||
>400 | 39 | 0.86 | 0.33–2.07 | 0.73 | ||||
<400 | 77 | 1 | ||||||
Surgical procedure | ||||||||
Open | 83 | 1.79 | 0.69–5.28 | 0.24 | ||||
Laparoscopic | 34 | 1 | ||||||
Spleen preserving | 18 | 0.56 | 0.12–1.87 | 0.37 | ||||
Non-spleen preserving | 99 | 1 | ||||||
Resection procedure | ||||||||
Hand-sewn | 47 | 0.88 | 0.36–2.07 | 0.78 | ||||
Stapler | 70 | 1 | ||||||
Pancreas texture | ||||||||
Soft | 75 | 1.65 | 0.68–4.35 | 0.28 | ||||
Hard | 42 | 1 | ||||||
Pancreas thickness (mm) | ||||||||
>12 | 56 | 0.71 | 0.30–1.64 | 0.42 | ||||
<12 | 61 | 1 | ||||||
Postoperative | D-Amy levels (U/l)—POD 1 | |||||||
>7238 | 33 | 5.07 | 2.07–12.78 | <0.01✝ | 1.21 | 0.31–4.75 | 0.78 | |
<7238 | 83 | 1 | 1 | |||||
D-Amy levels (U/l)—POD 3 | ||||||||
>737 | 51 | 4.99 | 2.04–13.25 | <0.01✝ | 3.91 | 1.02–16.36 | 0.046✝ | |
<737 | 65 | 1 | 1 | |||||
WBC (×103/μl)—POD 1 | ||||||||
>1.20 | 48 | 3.16 | 1.34-7.75 | <0.01✝ | 2.44 | 0.69–9.12 | 0.17 | |
<1.20 | 69 | 1 | 1 | |||||
WBC (×103/μl)—POD 3 | ||||||||
>1.40 | 34 | 2.59 | 1.07–6.29 | 0.04✝ | 1.03 | 0.27–3.73 | 0.96 | |
<1.40 | 83 | 1 | 1 | |||||
CRP (mg/dl)—POD 1 | ||||||||
>10 | 40 | 1.51 | 0.63–3.58 | 0.35 | ||||
<10 | 77 | 1 | ||||||
CRP (mg/dl)—POD 3 | ||||||||
>20 | 34 | 3.89 | 1.61–9.60 | <0.01✝ | 2.75 | 0.75–10.70 | 0.13 | |
<20 | 83 | 1 | 1 | |||||
Body temperature (°C)—POD 1 | ||||||||
>38.0 | 71 | 0.74 | 0.32–1.75 | 0.49 | ||||
<38.0 | 46 | 1 | ||||||
Body temperature (°C)—POD 3 | ||||||||
>38.0 | 14 | 0.47 | 0.07–1.87 | 0.31 | ||||
<38.0 | 103 | 1 | ||||||
Heart rate (bpm)—POD 1 | ||||||||
>100 | 38 | 2.05 | 0.85–4.88 | 0.11 | ||||
<100 | 79 | 1 | ||||||
Heart rate (bpm)—POD 3 | ||||||||
>100 | 13 | 4.35 | 1.32–14.81 | 0.02✝ | 3.84 | 0.77–21.40 | 0.10 | |
<100 | 104 | 1 | 1 | |||||