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Table 2 Comparison of pre-, intra-, and postoperative status between patients with and without POPF after distal pancreatectomy

From: The pancreas-to-muscle signal intensity ratio on T1-weighted MRI as a predictive biomarker for postoperative pancreatic fistula after distal pancreatectomy: a single-center retrospective study

   Patients with POPF
(n=29)
Patients without POPF
(n=88)
p-value
Preoperative Age (years) 67 (40–82) 67 (11–84) 0.87
Sex
 Male 18 (62.1) 50 (56.8) 0.67
 Female 11 (37.9) 38 (43.2)
BMI (kg/m2) 23.6 (17.6–32.2) 22.4 (16.2–32.2) 0.37
Pancreatic ductal adenocarcinoma 12 (41.4) 43 (48.9) 0.53
Location
 Body 14 (48.3) 54 (61.4) 0.28
 Tail 15 (51.7) 34 (38.6)
Pancreas-to-muscle SIR on T1-w MRI 1.64 (1.25–2.68) 1.35 (0.74–2.16) <0.01
Intraoperative Operative time (min) 284 (174–537) 264 (143–564) 0.13
Blood loss (ml) 190 (10–1910) 260 (0–1840) 0.84
Surgical procedure
 Open 23 (79.3) 60 (68.2) 0.35
 Laparoscopic 6 (20.7) 28 (31.8)
 Spleen preserving 3 (10.3) 15 (17.1) 0.56
 Non-spleen preserving 26 (89.7) 73 (82.9)
Resection procedure
 Hand-sewn 11 (37.9) 36 (40.9) 0.83
 Stapler 18 (62.1) 52 (59.1)
Pancreas texture
 Soft 21 (72.4) 54 (61.4) 0.37
 Hard 8 (27.6) 34 (38.6)
Pancreas thickness (mm) 11 (8–17) 12 (3–24) 0.46
Postoperative D-Amy levels (U/l)
 POD 1 7652 (108–34076) 1899 (42–61075) 0.02
 POD 3 1290 (42–16515) 403 (35–43873) <0.01
WBC (×103/μl)
 POD 1 12.6 (7.5–26.5) 11.1 (5.3–18.2) <0.01
 POD 3 13.3 (5.9–26.9) 11.3 (3.9–23.9) 0.048
CRP (mg/dl)
 POD 1 9.3 (1.8–15.4) 8.3 (0.2–17.5) 0.16
 POD 3 20.1 (8.0–33.5) 14.5 (0.3–26.5) <0.01
Body temperature (°C)
 POD 1 38.0 (37.1–39.4) 38.0 (36.9–39.3) 0.55
 POD 3 37.4 (36.1–38.9) 37.4 (36.2–39.4) 0.30
Heart rate (bpm)
 POD 1 98 (81–142) 92 (61–122) 0.07
 POD 3 88 (72–111) 82 (56–119) <0.01
  1. Data are expressed as median (range) or number of patients
  2. POPF Postoperative pancreatic fistula, BMI Body mass index, pancreas-to-muscle SIR on T1-w MRI the pancreas-to-muscle signal intensity ratio on unenhanced T1-weigthed magnetic resonance imaging, D-Amy drainage fluid amylase concentration, POD Postoperative day, WBC White blood cell, CRP C-reactive protein
  3. p< 0.05