Patients with POPF (n=29) | Patients without POPF (n=88) | p-value | ||
---|---|---|---|---|
Preoperative | Age (years) | 67 (40–82) | 67 (11–84) | 0.87 |
Sex | ||||
Male | 18 (62.1) | 50 (56.8) | 0.67 | |
Female | 11 (37.9) | 38 (43.2) | ||
BMI (kg/m2) | 23.6 (17.6–32.2) | 22.4 (16.2–32.2) | 0.37 | |
Pancreatic ductal adenocarcinoma | 12 (41.4) | 43 (48.9) | 0.53 | |
Location | ||||
Body | 14 (48.3) | 54 (61.4) | 0.28 | |
Tail | 15 (51.7) | 34 (38.6) | ||
Pancreas-to-muscle SIR on T1-w MRI | 1.64 (1.25–2.68) | 1.35 (0.74–2.16) | <0.01✝ | |
Intraoperative | Operative time (min) | 284 (174–537) | 264 (143–564) | 0.13 |
Blood loss (ml) | 190 (10–1910) | 260 (0–1840) | 0.84 | |
Surgical procedure | ||||
Open | 23 (79.3) | 60 (68.2) | 0.35 | |
Laparoscopic | 6 (20.7) | 28 (31.8) | ||
Spleen preserving | 3 (10.3) | 15 (17.1) | 0.56 | |
Non-spleen preserving | 26 (89.7) | 73 (82.9) | ||
Resection procedure | ||||
Hand-sewn | 11 (37.9) | 36 (40.9) | 0.83 | |
Stapler | 18 (62.1) | 52 (59.1) | ||
Pancreas texture | ||||
Soft | 21 (72.4) | 54 (61.4) | 0.37 | |
Hard | 8 (27.6) | 34 (38.6) | ||
Pancreas thickness (mm) | 11 (8–17) | 12 (3–24) | 0.46 | |
Postoperative | D-Amy levels (U/l) | |||
POD 1 | 7652 (108–34076) | 1899 (42–61075) | 0.02✝ | |
POD 3 | 1290 (42–16515) | 403 (35–43873) | <0.01✝ | |
WBC (×103/μl) | ||||
POD 1 | 12.6 (7.5–26.5) | 11.1 (5.3–18.2) | <0.01✝ | |
POD 3 | 13.3 (5.9–26.9) | 11.3 (3.9–23.9) | 0.048✝ | |
CRP (mg/dl) | ||||
POD 1 | 9.3 (1.8–15.4) | 8.3 (0.2–17.5) | 0.16 | |
POD 3 | 20.1 (8.0–33.5) | 14.5 (0.3–26.5) | <0.01✝ | |
Body temperature (°C) | ||||
POD 1 | 38.0 (37.1–39.4) | 38.0 (36.9–39.3) | 0.55 | |
POD 3 | 37.4 (36.1–38.9) | 37.4 (36.2–39.4) | 0.30 | |
Heart rate (bpm) | ||||
POD 1 | 98 (81–142) | 92 (61–122) | 0.07 | |
POD 3 | 88 (72–111) | 82 (56–119) | <0.01✝ |