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Table 1 Comparison of clinical characteristics of patients between DEB-TACE and cTACE

From: Callispheres® drug-eluting beads transarterial chemoembolization might be an efficient and safety down-staging therapy in unresectable liver cancer patients

Items

DEB-TACE (N = 80)

cTACE (N = 100)

p-value

Age (years), mean ± SD

50.8 ± 7.4

51.5 ± 6.8

0.510

Gender, no. (%)

 Male

63 (78.6%)

78 (78%)

0.903

 Female

17 (21.4%)

22 (22%)

 

Etiology, no. (%)

 HBV

53 (66.3%)

70 (70%)

0.897

 HCV

10 (12.5%)

12 (12%)

 

 Alcohol

8 (10%)

10 (10%)

 

 Others

9 (11.2%)

8 (8%)

 

Number of tumors, no. (%)

 1–3

65 (81.2%)

83 (83%)

0.760

 ≥ 4

15 (18.8%)

17 (17%)

 

Largest tumor diameter (cm), mean ± SD

8.69 ± 0.44

8.35 ± 0.45

0.605

Portal vein invasion, no. (%)

13 (16.25%)

18 (18%)

0.757

Lymphadenectasis, no. (%)

15 (18.8%)

20 (20%)

0.833

Distant metastasis, no. (%)

8 (10%)

12 (12%)

0.671

Liver involvement, no. (%)

 ≤ 50%

7 (8.7%)

15 (15%)

0.419

 50–70%

60 (75%)

68 (68%)

 

 ≥ 70%

13 (16.3%)

17 (17%)

 

ECOG score, no. (%)

 0–1

73 (91.3%)

85 (85%)

0.203

 2

7 (8.7%)

15 (15%)

 

BCLC stage, no. (%)

 A

23 (28.7%)

27 (27%)

0.684

 B

45 (56.3%)

53 (53%)

 

 C

12 (15%)

20 (20%)

 

Child-Pugh stage, no. (%)

 A

70 (87.5%)

83 (83%)

0.401

 B

10 (12.5%)

17 (17%)

 

Cycles of DEB-TACE, no. (%)

 1–2

54 (67.5%)

76 (76%)

0.816

 ≥ 3

26 (32.5%)

34 (34%)

 

Conversion rate, no. (%)

 Yes

15 (18.8%)

8 (8%)

0.032*

 No

65 (81.2%)

92 (92%)

 
  1. SD standard deviation, HB hepatitis B, HCC hepatocellular carcinoma, ECOG Eastern Cooperative Oncology Group, BCLC Barcelona clinic liver cancer, DEB-TACE drug-eluting bead transarterial chemoembolization
  2. *p < 0.05