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Table 4 COX regression analysis of risk factors for disease-free survival of right-sided colon cancer patients in the PSM cohort

From: Clinical implication of the advanced lung cancer inflammation index in patients with right-sided colon cancer after complete mesocolic excision: a propensity score-matched analysis

Variables

Disease-free survival

Univariate

Multivariate

HR (95%CI)

P value

HR (95%CI)

P value

Age (>60 vs. ≤60, years)

1.370 (0.846-2.218)

0.200

1.516 (0.934-2.460)

0.092

Gender (male vs. female)

1.397 (0.854-2.283)

0.183

  

Preoperative CEA (>5 vs. ≤5, ng/ml)

1.600 (0.990-2.584)

0.055

  

Preoperative CA19-9 (>37 vs. ≤37, U/ml)

2.268 (1.362-3.778)

0.002

1.821 (1.066-3.112)

0.028

Diabetes

0.746 (0.357-1.562)

0.437

  

Hypertension

1.303 (0.787-2.158)

0.303

  

Tumor location (ileocecal /ascending colon vs. hepatic flexure colon)

1.400 (0.862-2.276)

0.174

  

Operative time (min)

1.002 (0.997-1.007)

0.389

  

Estimated blood loss (ml)

0.997 (0.992-1.001)

0.181

  

pT stage (T3/4 vs. T1/2)

5.493 (0.762-39.579)

0.091

3.416(0.447-26.102)

0.236

pN stage (N+ vs. N0)

3.021 (1.814-5.032)

<0.001

2.373 (1.219-4.662)

0.011

Tumor differentiation (grade 3+4 vs. 1+2)

1.954 (0.933-4.089)

0.076

  

Histopathology (mucinous/signet ring cell adenocarcinoma vs. adenocarcinoma)

1.257 (0.763-2.071)

0.370

  

Lymphovascular invasion

2.689 (1.550-4.665)

<0.001

2.271 (1.289-4.001)

0.005

Nerval invasion

1.603 (0.818-3.142)

0.169

  

Postoperative complications

0.822 (0.463-1.460)

0.503

  

Adjuvant chemotherapy

2.625 (1.375-5.010)

0.003

0.912 (0.383-2.170)

0.835

ALI (low vs. high)

2.286 (1.372-3.806)

0.001

2.389 (1.434-3.982)

0.001

  1. HR hazard ratio, CI confidence interval, ALI advanced lung cancer inflammation index, CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen 19-9