Table 3 COX regression analysis of risk factors for overall survival of right-sided colon cancer patients in the PSM cohort

Age (>60 vs. ≤60, years)

1.690 (1.045-2.732)

0.032

1.954 (1.203-3.175)

0.007

Gender (male vs. female)

1.281 (0.792-2.071)

0.313

Preoperative CEA (>5 vs. ≤5, ng/ml)

1.475 (0.920-2.365)

0.106

Preoperative CA19-9 (>37 vs. ≤37, U/ml)

2.621 (1.604-4.283)

<0.001

1.964 (1.168-3.303)

0.011

Diabetes

1.066 (0.559-2.031)

0.846

Hypertension

1.323 (0.806-2.172)

0.268

Tumor location (ileocecal /ascending colon vs. hepatic flexure colon)

1.287 (0.800-2.072)

0.298

Operative time (min)

1.000 (0.995-1.005)

0.980

Estimated blood loss (ml)

0.997 (0.993-1.002)

0.237

pT stage (T3/4 vs. T1/2)

5.441 (0.755-39.186)

0.093

2.960(0.387-22.638)

0.296

pN stage (N+ vs. N0)

4.243 (2.478-7.267)

<0.001

3.266 (1.583-6.737)

<0.001

Tumor differentiation (grade 3+4 vs. 1+2)

1.343 (0.581-3.103)

0.490

Histopathology (mucinous/signet ring cell adenocarcinoma vs. adenocarcinoma)

0.704 (0.427-1.164)

0.169

Lymphovascular invasion

2.273 (1.281-4.033)

0.005

1.738 (0.958-3.154)

0.069

Nerval invasion

2.536 (1.407-4.569)

0.002

1.451 (0.776-2.710)

0.243

Postoperative complications

1.167 (0.694-1.964)

0.560

Adjuvant chemotherapy

3.356 (1.665-6.764)

0.001

0.918 (0.354-2.382)

0.860

ALI (low vs. high)

3.106 (1.815-5.316)

<0.001

3.305 (1.927-5.667)

<0.001