Characteristics | Before PSM | After PSM | ||||||
---|---|---|---|---|---|---|---|---|
Total (n = 441) | Low-ALI | High-ALI | P value | Total (n = 360) | Low-ALI | High-ALI | P value | |
(n = 236) | (n = 205) | (n = 180) | (n = 180) | |||||
Age, n (%) | Â | Â | Â | 0.015 | Â | Â | Â | 0.399 |
 ≤60 years | 207 (46.9) | 98 (41.5) | 109 (53.2) |  | 186 (51.7) | 89 (49.4) | 97 (53.9) |  |
 >60 years | 234 (53.1) | 138 (58.5) | 96 (46.8) |  | 174 (48.3) | 91 (50.6) | 83 (46.1) |  |
Gender, n (%) | Â | Â | Â | 0.815 | Â | Â | Â | 0.672 |
 Male | 234 (53.1) | 124 (52.5) | 110 (53.7) |  | 194 (53.9) | 95 (52.8) | 99 (55.0) |  |
 Female | 207 (46.9) | 112 (47.5) | 95 (46.3) |  | 166 (46.1) | 85 (47.2) | 81 (45.0) |  |
ASA classification, n (%) | Â | Â | Â | 0.203 | Â | Â | Â | 0.115 |
 1+2 | 410 (93.0) | 216 91.5) | 194 (94.6) |  | 332 (92.2) | 162 (90.0) | 170 (94.4) |  |
 3+4 | 31 (7.0) | 20 (8.5) | 11 (5.4) |  | 28 (7.8) | 18 (10.0) | 10 (5.6) |  |
Preoperative anemia | 275 (62.4) | 165 (69.9) | 110 (53.7) | <0.001 | 223 (61.9) | 125 (69.4) | 98 (54.4) | 0.003 |
Preoperative CEA, n (%) | Â | Â | Â | 0.430 | Â | Â | Â | 0.748 |
 ≤5 ng/ml | 271 (61.5) | 141 (59.7) | 130 (63.4) |  | 213 (59.2) | 105 (58.3) | 108 (60.0) |  |
 >5 ng/ml | 170 (38.5) | 95 (40.3) | 75 (36.6) |  | 147 (40.8) | 75 (41.7) | 72 (40.0) |  |
Preoperative CA19-9, n (%) | Â | Â | Â | 0.119 | Â | Â | Â | 0.895 |
 ≤37 U/ml | 347 (78.7) | 179 (75.8) | 168 (82.0) |  | 289 (78.7) | 145 (80.6) | 144 (80.0) |  |
 >37 U/ml | 94 (21.3) | 57 (24.2) | 37 (18.0) |  | 71 (21.3) | 35 (19.4) | 36 (20.0) |  |
Diabetes, n (%) | 101 (15.3) | 7 (14.6) | 94 (15.3) | 0.889 | 53 (14.7) | 28 (15.6) | 25 (13.9) | 0.655 |
Hypertension, n (%) | 186 (28.1) | 14 (29.2) | 172 (28.1) | 0.869 | 102 (28.3) | 47 (26.1) | 55 (30.6) | 0.349 |
Surgical approach, n (%) | Â | Â | Â | 0.001 | Â | Â | Â | 0.004 |
 Laparoscopic | 317 (71.9) | 154 (65.3) | 163 (79.5) |  | 255 (29.2) | 115 (63.9) | 140 (77.8) |  |
 Open | 124 (28.1) | 82 (34.7) | 42 (20.5) |  | 105 (70.8) | 65 (36.1) | 40 (22.2) |  |
Tumor location, n (%) | Â | Â | Â | 0.242 | Â | Â | Â | 0.598 |
 Ileocecal /ascending colon | 217 (49.2) | 110 (46.6) | 107 (52.2) |  | 179 (49.7) | 87 (48.3) | 92 (51.1) |  |
 Hepatic flexure colon | 224 (50.8) | 126 (53.4) | 98 (47.8) |  | 181 (50.3) | 93 (51.7) | 88 (48.9) |  |
Total retrieved LNs | Â | Â | Â | 0.404 | Â | Â | Â | 0.723 a |
 <12 | 12 (2.7) | 5 (2.1) | 7 (3.4) |  | 8 (2.2%) | 3 (1.7%) | 5 (2.8%) |  |
 ≥12 | 429 (97.3) | 231 (97.9) | 198 (96.6) |  | 352 (97.8%) | 177 (98.3%) | 175 (97.2%) |  |
Operative time, n (%) | Â | Â | Â | 0.527 | Â | Â | Â | 0.398 |
 ≤205 min | 208 (47.2) | 108 (45.8) | 100 (48.8) |  | 166 (46.1) | 79 (43.9) | 87 (48.3) |  |
 >205 min | 233 (52.8) | 128 (54.9) | 105 (51.2) |  | 194 (53.9) | 101 (56.1) | 93 (51.7) |  |
Estimated blood loss, n (%) | Â | Â | Â | 0.221 | Â | Â | Â | 0.292 |
 ≤55 ml | 225 (51.0) | 114 (48.3) | 111 (54.1) |  | 182 (50.6) | 86 (47.3) | 96 (53.3) |  |
 >55 ml | 216 (49.0) | 122 (51.7) | 94 (45.9) |  | 178 (49.4) | 94 (52.2) | 84 (46.7) |  |
pT stage, n (%) | Â | Â | Â | <0.001 | Â | Â | Â | 0.684 |
 T1+2 | 48 (10.9) | 12 (5.1) | 36 (17.6) |  | 26 (10.9) | 12 (6.7) | 14 (7.8) |  |
 T3+4 | 393 (89.1) | 224 (94.9) | 169 (82.4) |  | 334 (89.1) | 168 (93.3) | 166 (92.2) |  |
pN stage, n (%) | Â | Â | Â | 0.413 | Â | Â | Â | 0.590 |
 N0 | 248 (56.2) | 128 (54.2) | 120 (58.5) |  | 205 (56.9) | 100 (55.6) | 105 (58.3) |  |
 N+ | 193 (43.8) | 108 (45.8) | 85 (44.3) |  | 155 (43.1) | 80 (44.4) | 75 (41.7) |  |
pTNM stage, n (%) | Â | Â | Â | 0.004 | Â | Â | Â | 0.762 |
 I | 39 (9.5) | 11 (8.3) | 28 (9.6) |  | 25 (9.5) | 11 (6.1) | 14 (7.8) |  |
 II | 209 (46.5) | 117 (54.2) | 92 (45.7) |  | 180 (46.5) | 89 (49.4) | 91 (50.6) |  |
 III | 193 (44.0) | 108 (37.5) | 85 (44.7) |  | 155 (44.0) | 80 (44.5) | 75 (41.7) |  |
Tumor differentiation, n (%) | Â | Â | Â | 0.014 | Â | Â | Â | 0.673 |
 Grade 1+2 | 399 (90.5) | 206 (87.3) | 193 (94.1) |  | 336 (93.3) | 167 (92.8) | 169 (93.9) |  |
 Grade 3+4 | 42 (9.5) | 30 (12.7) | 12 (5.9) |  | 24 (6.7) | 13 (7.2) | 11 (6.1) |  |
Histopathology, n (%) | Â | Â | Â | 0.960 | Â | Â | Â | 0.521 |
 Adenocarcinoma | 263 (59.6) | 141 (59.7) | 122 (59.5) |  | 210 (90.5) | 108 (60.0) | 102 (56.7) |  |
 Mucinous/signet ring cell adenocarcinoma | 178 (40.4) | 95 (40.3) | 83 (40.5) |  | 150 (9.5) | 72 (40.0) | 78 (43.3) |  |
Nerval invasion, n (%) | 46 (16.3) | 26 (11.0) | 20 (9.8) | 0.666 | 36 (10.0) | 17 (9.4) | 19 (10.6) | 0.725 |
Lymphovascular invasion, n (%) | 67 (19.2) | 40 (16.9) | 27 (13.2) | 0.270 | 48 (13.3) | 24 (13.3) | 24 (13.3) | 0.270 |
Adjuvant chemotherapy | 295 (66.9) | 165 (69.9) | 130 (63.4) | 0.148 | 242 (67.2) | 123 (68.3) | 119 (66.1) | 0.653 |
Postoperative hospital stays, mean (SD) | 8.88 (5.35) | 9.61 (5.44) | 8.23 (5.47) | 0.009 | 8.82 (5.30) | 9.53 (4.97) | 8.14 (5.528) | 0.014 |