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Table 2 MINORS checklist for included studies

From: Efficacy and safety of triplet chemotherapy plus anti-EGFR agents in metastatic colorectal cancer: a systematic review and meta-analysis

Study

Garufi

Sougklakos

ASSENAT

Saridaki

Folprecht

Fornaro

Bendell

Pietrantonio

Cremolini

Modest

Ogata

Samalin

Deng

Tsuji

Methodological items for non-randomized studies

 A clearly stated aim

2

2

2

2

2

2

2

2

2

2

2

2

2

2

 Inclusion of consecutive patients

2

2

2

2

2

2

2

2

2

2

2

2

2

2

 Prospective collection of data

2

2

2

2

2

2

2

2

2

2

1

1

2

2

 Endpoints appropriate to the aim of study

2

2

2

2

2

2

2

2

2

2

2

2

2

2

 Unbiased assessment of the study endpoint

2

2

2

2

2

2

2

2

2

2

2

2

2

2

 Follow-up period appropriate to the aim of the study

2

2

2

2

2

2

2

2

2

2

2

2

2

2

 Loss to follow up less than 5%

2

2

2

2

2

2

2

2

2

2

2

2

2

2

 Prospective calculation of the study size

2

0

2

2

0

2

2

0

2

0

0

0

2

0

Additional criteria for comparative studies

 An adequate control group

-

-

-

-

2

-

-

-

2

-

2

-

-

2

 Contemporary groups

-

-

-

-

2

-

-

-

2

-

2

-

-

2

 Baseline equivalence of groups

-

-

-

-

2

-

-

-

2

-

2

-

-

2

 Adequate statistical analyses

-

-

-

-

2

-

-

-

2

-

2

-

-

2

 Total

16

14

16

16

22

16

16

14

24

14

21

13

16

22