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Table 4 Associations between peripheral blood markers and irAEs

From: Absolute eosinophil count may be an optimal peripheral blood marker to identify the risk of immune-related adverse events in advanced malignant tumors treated with PD-1/PD-L1 inhibitors: a retrospective analysis

Blood parameter

Cutoff value

irAEs, n (%)

P value

NLR

8.58

 

0.041*

Low (n = 86)

 

51/86 (59.3%)

High (n = 9)

 

2/9 (22.2%)

 

PLR

180.68

 

0.089

Low (n = 50)

 

32/50 (64%)

High (n = 45)

 

21/45 (46.7%)

 

AEC

0.045 × 109/L

 

0.010*

Low (n = 22)

 

7/22 (31.8%)

High (n = 73)

 

46/73 (63%)

  1. Abbreviations: NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, AEC Absolute eosinophil count
  2. *P < 0.05.