Skip to main content

Table 1 Patient characteristics (n = 95)

From: Absolute eosinophil count may be an optimal peripheral blood marker to identify the risk of immune-related adverse events in advanced malignant tumors treated with PD-1/PD-L1 inhibitors: a retrospective analysis

Patient characteristics

Patients treated with anti-PD-1/PD-L1 therapy (n = 95), n (%)

Age at initiation of anti-PD-1/PD-L1 therapy (years)

 Median

62

 Range

30–80

Sex

 Male

66 (69.5)

 Female

29 (30.5)

ECOG

 0

25 (26.3)

 1

61 (64.2)

 2

9 (9.5)

Tumor type

 Lung cancer (NSCLC: n = 20, small cell lung cancer: n = 5)

25 (26.3)

 Esophageal carcinoma

17 (17.9)

 Liver cancer

11 (11.6)

 Head and neck cancer

8 (8.4)

 Genital system cancer

6 (6.3)

 Colorectal cancer

7 (7.4)

 Gastric carcinoma

7 (7.4)

 Urogenital carcinoma

4 (4.2)

 Cutaneous soft tissue carcinoma

3 (3.2)

 Melanoma

2 (2.1)

 Gallbladder carcinoma and bile duct carcinoma

2 (2.1)

 Others

3 (3.2)

TNM clinical classification

 III

29 (30.5)

 IV

58 (61.1)

 Unknown

7 (7.4)

Treatment lines at initiation of anti-PD-1/PD-L1 therapy

 First-line

36 (37.9)

 Second-line

29 (30.5)

 Third-line and above

30 (31.6)

Treatment

 Immunotherapy

38 (40)

 Immunotherapy + targeted therapy

22 (23.2)

 Immunotherapy + chemotherapy

31 (32.6)

 Immunotherapy + chemotherapy + targeted therapy

4 (4.2)

Baseline ACE

 Mean ± SD

0.12 ± 0.017

Baseline PLR

 Mean ± SD

204.899 ± 102.712

Baseline NLR

 Median

3.381

 Range

1.021–40.625