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Table 2 Univariate and multivariate analyses of variables associated with station 4R lymph node metastasis

From: Prognostic significance of 4R lymph node dissection in patients with right primary non-small cell lung cancer

Variables

No.

Univariate analyses

Multivariate analyses

Station 4R metastasis no. (%)

P

Positive

Negative

OR

95% CI

P

Age (year)

   

0.208

   

 < 65

1312

185 (14.1)

1127 (85.9)

    

 ≥ 65

551

65 (11.8)

486 (88.2)

    

Gender

   

0.273

   

 Female

816

101 (12.4)

715 (87.6)

    

 Male

1047

149 (14.2)

898 (85.8)

    

Smoking history

   

1.000

   

 Yes

1080

145 (13.4)

935 (86.6)

    

 No

783

105 (13.4)

678 (86.6)

    

Surgical approaches

   

< 0.001

   

 Thoracoscopic surgery

860

78 (9.1)

782 (90.9)

 

1

  

 Thoracotomy

1003

172 (17.2)

831 (82.8)

 

1.19

0.81–1.77

0.362

Tumor location

   

0.013

   

 Upper lobe

994

154 (15.5)

840 (84.5)

 

1

  

 Middle lobe

224

21 (9.4)

203 (90.6)

 

0.46

0.24–0.84

0.016

 Lower lobe

645

75 (11.6)

570 (88.4)

 

0.44

0.29–0.65

< 0.001

Histological type

   

0.305

   

 Adenocarcinoma

1265

178 (14.1)

1087 (85.9)

    

 Squamous cell carcinoma

397

44 (11.1)

353 (88.9)

    

 Others

201

28 (13.9)

173 (86.1)

    

pT stage

   

< 0.001

   

 T1a

169

8 (4.7)

161 (95.3)

 

1

  

 T1b

557

52 (9.3)

505 (90.7)

 

1.73

0.73–4.63

0.241

 T1c

524

79 (15.1)

445 (84.9)

 

2.79

1.21–7.38

0.025

 T2a

252

39 (15.5)

213 (84.5)

 

2.65

1.06–7.39

0.047

 T2b

157

26 (16.6)

131 (83.4)

 

2.36

0.86–7.05

0.106

 T3

147

34 (23.1)

113 (76.9)

 

4.89

1.87–14.07

0.002

 T4

57

12 (21.1)

45 (78.9)

 

4.17

1.28–14.05

0.019

Station 2 metastasis

116

84 (72.4)

32 (27.6)

< 0.001

11.19

6.67–19.06

< 0.001

Station 3 metastasis

139

93 (66.9)

46 (33.1)

< 0.001

6.06

3.79–9.72

< 0.001

Station 7 metastasis

207

105 (50.7)

102 (49.3)

< 0.001

5.02

3.31–7.63

< 0.001

Station 8 metastasis

38

21 (55.3)

17 (44.7)

< 0.001

1.43

0.59–3.48

0.423

Station 9 metastasis

53

28 (52.8)

25 (47.2)

< 0.001

1.44

0.65–3.13

0.355

Station 10 metastasis

220

93 (42.3)

127 (57.7)

< 0.001

2.15

1.41–3.24

< 0.001

Station 11 metastasis

248

107 (43.2)

141 (56.8)

< 0.001

2.58

1.71–3.87

< 0.001