Fig. 2

Construction of the risk predictive model using the differentially expressed IRG pairs. Univariate Cox regression analysis (A) and multivariate analysis (B) to determine the risk effects of IRG pairs in the TCGA dataset. C, D The establishment of the prognostic model based on LASSO penalized Cox analysis. E The optimal cutoff (1.433) of the risk model was used to classify patients into low- and high-risk groups. F Time-dependent ROC analysis for predicting the overall survival of patients in the TCGA cohort using the risk score