Transthoracic, thoracoabdominal, and transabdominal surgical approaches for gastric cardia adenocarcinomas: a survival evaluation based on a cohort of 7103 patients

Table 1 The distribution of clinicopathological characteristics in 7103 GCA patients treated with different surgical approaches, n (%)

Characteristics	No. of patients examined	Transthoracic (n = 5657)		Thoracoabdominal (n = 942)		Transabdominal (n = 504)		p-Value
Sex								0.24
Male	5600	4439	(79)	762	(81)	399	(79)
Female	1503	1218	(21)	180	(19)	105	(21)
Age (years)								< 0.001*
< 40	64	44	(1)	15	(2)	5	(1)
40–49	550	430	(7)	92	(10)	28	(5)
50–59	2061	1692	(30)	258	(27)	111	(22)
60–69	3145	2487	(44)	408	(43)	250	(50)
70–79	1224	966	(17)	161	(17)	97	(19)
≥ 80	59	38	(1)	8	(1)	13	(3)
Tumor stage								< 0.001†
0	30	24	(1)	4	(1)	2	(1)
I	328	250	(4)	38	(4)	40	(8)
II	2991	2448	(43)	397	(42)	146	(29)
III	3541	2813	(50)	454	(48)	274	(54)
IV	213	122	(2)	49	(5)	42	(8)
N stage								0.06
N0	2737	2218	(39)	344	(36)	175	(35)
N1	4366	3439	(61)	598	(64)	329	(65)

*Significant difference between the transthoracic and thoracoabdominal groups in the < 40 subgroup; significant difference between the thoracoabdominal and transabdominal groups in the 40 subgroups; significant difference between the transthoracic and transabdominal groups in the 50 subgroups and 60 subgroups; no significant difference among all three groups in the 70 subgroups; significant difference between the transabdominal and transthoracic and between the transabdominal and thoracoabdominal groups in the 80 subgroups
†No significant difference among all three groups among patients with stages 0 and 3 disease; significant difference between the transabdominal and transthoracic and between the transabdominal and thoracoabdominal groups among patients with stages 1 and 2 disease; significant difference between the transthoracic and thoracoabdominal and between the transthoracic and transabdominal groups among patients with stage 4 disease

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