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Table 2 Relationships of VDAC1 expression and marker genes of immune cells in TIMER

From: Overexpressed VDAC1 in breast cancer as a novel prognostic biomarker and correlates with immune infiltrates

Cell type Gene marker None Purity
Cor p Cor p
B cell CD19 −0.154 *** −0.083 **
CD20(KRT20) 0.114 *** 0.126 ***
CD38 −0.073 * 0.011 0.719
CD8 + T cell CD8A −0.125 *** −0.04 0.203
CD8B −0.191 *** −0.111 ***
Tfh BCL6 −0.067 * −0.033 0.305
ICOS −0.001 0.967 0.092 **
CXCR5 −0.176 *** −0.097 **
Th1 T-bet (TBX21) −0.174 *** −0.096 **
STAT4 −0.104 *** −0.001 0.970
IL12RB2 −0.033 0.269 0.029 0.357
WSX1(IL27RA) −0.245 *** −0.191 ***
STAT1 0.173 *** 0.218 ***
IFN-γ (IFNG) −0.091 ** −0.024 0.449
TNF-α (TNF) −0.059 0.050 −0.01 0.762
Th2 GATA3 0.167 *** 0.116 ***
CCR3 −0.049 0.103 −0.011 0.720
STAT6 −0.064 * −0.055 0.082
STAT5A −0.165 *** −0.124 ***
Th9 TGFBR2 −0.07 * 0.036 0.261
IRF4 −0.124 *** −0.024 0.454
PU.1(SPI1) −0.226 *** −0.172 ***
Th17 STAT3 0.107 *** 0.117 ***
IL-21R −0.108 *** −0.015 0.636
IL-23R −0.02 0.505 0.038 0.233
IL-17A −0.055 0.067 −0.019 0.559
Th22 CCR10 −0.314 *** −0.293 ***
AHR 0.074 * 0.131 ***
Treg FOXP3 −0.003 0.909 0.087 **
CD25(IL2RA) 0.007 0.814 0.099 **
CCR8 0.153 *** 0.223 ***
T cell exhaustion PD-1 (PDCD1) −0.178 *** −0.112 ***
CTLA4 −0.057 0.058 0.026 0.419
LAG3 −0.112 *** −0.07 *
TIM-3 (HAVCR2) 0.009 0.759 0.085 **
Macrophage CD68 0.000 0.997 0.069 *
CD11b (ITGAM) −0.076 * −0.028 0.378
M1 INOS (NOS2) −0.115 *** −0.107 ***
IRF5 0.006 0.850 0.025 0.430
COX2(PTGS2) −0.133 *** −0.058 0.066
M2 CD163 0.023 0.446 0.088 **
ARG1 −0.025 0.411 0.026 0.405
MRC1 −0.039 0.198 0.048 0.134
MS4A4A 0.006 0.844 0.09 **
TAM CCL2 −0.08 ** −0.009 0.767
CD80 0.122 *** 0.177 ***
CD86 −0.012 0.692 0.068 *
CCR5 −0.073 * 0.022 0.491
Monocyte CD14 −0.225 *** −0.181 ***
CD16(FCGR3B) 0.141 *** 0.163 ***
CD115 (CSF1R) −0.186 *** −0.123 ***
Neutrophil CD66b (CEACAM8) −0.101 *** −0.099 **
CD15(FUT4) −0.09 ** 0.002 0.952
CD11b (ITGAM) −0.076 * −0.028 0.378
Natural killer cell XCL1 −0.138 *** −0.059 0.064
CD7 −0.204 *** −0.141 ***
KIR3DL1 −0.091 ** −0.034 0.280
Dendritic cell CD1C(BDCA-1) −0.217 *** −0.149 ***
CD141(THBD) −0.136 *** −0.101 **
CD11c (ITGAX) −0.101 *** −0.033 0.305