Table 1 Main characteristics of all studies included in the meta-analysis
Author | Year | Country | Enrollment | Type | HIPEC group (n) | Control group (n) | HIPEC characteristics | Control characteristics | HR 95% CI | |
|---|---|---|---|---|---|---|---|---|---|---|
Technique | Time (min) | |||||||||
Franko | 2010 | American | 2001–2007 | Cohort | 67 | 38 | Close | 100 | PC | 0.42 (0.19–0.91) |
Cashin | 2012 | Sweden | 1996–2010 | Cohort | 69 | 57 | Open | 30 | CRS + SPIC | 0.60 (0.36–0.99) |
Chen | 2020 | China | 2008–2016 | Randomized | 14 | 14 | Close | 90 | HIPEC + dCRS | 0.98 (0.57–1.32) |
Razenberg | 2015 | Netherlands | 2005–2012 | Cohort | 297 | 1980 | NR | NR | PC | 0.36 (0.36–0.43) |
Huang | 2014 | China | 2005–2013 | Cohort | 33 | 29 | Close | 90 | CRS | 0.47 (0.25–0.85) |
Gervais | 2013 | Canada | 2004–2011 | Cohort | 25 | 15 | Close | 30 | PC | 0.21 (0.12–0.52) |
Elias | 2009 | France | 1998–2003 | Cohort | 48 | 48 | Open | 30 | PC | 0.35 (0.19–0.64) |
Verwaal | 2008 | Netherlands | 1998–2001 | Randomized | 54 | 51 | Open | 90 | PC | 0.57 (0.36–0.93) |
Baratti | 2020 | Italy | 2012–2018 | Cohort | 48 | 48 | Close | 60 | CRS | 0.73 (0.47–1.15) |
Quénet | 2021 | France | 2008–2014 | Randomized | 133 | 132 | NR | 30 | CRS | 0.99 (0.62–1.57) |